Halliwell B, Gutteridge J M
Mol Aspects Med. 1985;8(2):89-193. doi: 10.1016/0098-2997(85)90001-9.
The study of free radical reactions is not an isolated and esoteric branch of science. A knowledge of free radical chemistry and biochemistry is relevant to an understanding of all diseases and the mode of action of all toxins, if only because diseased or damaged tissues undergo radical reactions more readily than do normal tissues. However it does not follow that because radical reactions can be demonstrated, they are important in any particular instance. We hope that the careful techniques needed to assess the biological role of free radicals will become more widely used.
对自由基反应的研究并非科学中一个孤立且深奥的分支。自由基化学和生物化学知识与理解所有疾病及所有毒素的作用方式都相关，这仅仅是因为患病或受损组织比正常组织更易发生自由基反应。然而，仅仅因为能证明自由基反应的存在，并不意味着它们在任何特定情况下都很重要。我们希望评估自由基生物学作用所需的精细技术能得到更广泛的应用。
