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[全髋关节置换术后髋臼骨缺损翻修的重建技术及中期临床疗效]

[The reconstruction techniques and mid-term clinical outcomes of hip revision for acetabular bone defect after total hip arthroplasty].

作者信息

Zhang B H, Fu J, Zhang G Q, Zhou Y G, Chen J Y, Chai W

机构信息

Senior Department of Orthopaedics, the Forth Medical Center of Chinese People's Liberation Army General Hospital, National Clinical Research Center for Orthopaedics, Sports Medicine and Rehabilitation, Beijing 100048, China.

Department of Orthopaedics, the First Medical Center of Chinese People's Liberation Army General Hospital, National Clinical Research Center for Orthopaedics, Sports Medicine and Rehabilitation, Beijing 100853, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2024 Sep 1;62(9):836-846. doi: 10.3760/cma.j.cn112139-20240514-00243.

Abstract

To analyze three reconstruction techniques and mid-term clinical outcomes of hip revision for acetabular bone defect after total hip arthroplasty (THA). This is a retrospective case series study. Included in the study were 109 patients (109 hips) with acetabular bone defect after THA reconstructions in hip revisions from January 2015 to December 2021 in the Senior Department of Orthopaedics, the Forth Medical Center of Chinese People's Liberation Army General Hospital and the Department of Orthopaedics, the First Medical Center of Chinese People's Liberation Army General Hospital. According to the preoperative simulated surgeries and different bone defect reconstruction techniques, patients were divided into a normal cup group, an augment group or a triflange group,respectively. There were 54 patients (54 hips) in the normal cup group, reconstructed with the uncemented porous metal cup (including Jumbo cup), with 23 males and 31 females, aged (59.6±9.9) years (range:32 to 76 years); 44 patients (44 hips) in the augment group, reconstructed with the individualized three-dimensional (3D) printed porous metal augment and uncemented porous metal cup, with 18 males and 26 females, aged (52.8±13.6) years(range:17 to 76 years); 11 patients (11 hips) in the triflange group, reconstructed by the individualized 3D printed porous metal triflange cup, with 5 males and 6 females, aged (59.4±11.2) years (range: 43 to 78 years). Radiographic results, including rotation center height, rotation center offset, and leg length discrepancy (LLD) and clinical results, including Harris hip score (HHS) and visual analogue scale(VAS) were evaluated outpatient at 3, 6, 12 months after the operation and annually thereafter. The last follow-up was completed in March 2024, and all parameters at the last follow-up and before the operation were compared. Paired sample test and repeated measurement ANOVA were used for the radiographic and clinical parameters before and after the operation. All hip revisions for patients with acetabular bone defect after THA were completed and followed for more than two years. The follow-up time of the normal cup group was (6.5±1.7) years (range: 2.8 to 9.3 years), and that of the augment group was (6.0±1.3) years (range: 3.5 to 9.0 years). The follow-up time of the triflange group was (2.8±0.6) years (range: 2.0 to 3.8 years). At the last follow-up, the rotation center height, rotation center offset and LLD of 54 hips in the normal cup group were (24.2±5.6) mm, (29.1±5.5) mm and (4.6±3.3) mm, respectively, and the rotation center height and LLD were significantly lower than those of the preoperative hips (=9.671, <0.01; =6.073, <0.01). In the augment group, the rotational center height, the rotation center offset and the LLD of 44 hips were (22.4±9.0) mm, (25.4±5.5) mm and (6.0±4.0) mm, respectively, which were significantly lower than those of the preoperative hips (=9.071, <0.01; =11.345, <0.01; =4.927, <0.01). In the triflange group, the rotational center height, the rotation center offset and LLD of 11 hips were (22.7±6.0) mm,(30.9±8.0) mm and (5.3±2.2) mm, respectively, and the rotation center height and LLD were significantly lower than those of the preoperative hips (=2.716, =0.022; =6.226, <0.01). At the last follow-up, fractures occurred in 3 patients and dislocation occurred in 1 patient in the normal cup group, and fracture reduction and closed reduction were administered under anesthesia, respectively. In the augment group, dislocation occurred in 1 patient and open reduction under anesthesia was performed. The HHS and VAS of the three groups improved significantly after surgery and the differences were statistically significant (all <0.01). There was no complication in the triflange group. The X-ray at the last follow-up showed that all prostheses and augments were in stable positions and no loosening or migration was observed. For patients with acetabular bone defect after THA undergoing hip revisions, preoperative surgical simulation and rehearsal could help surgeons choose convenient and efficient reconstruction techniques. The targeted selection of Jumbo cup, individualized 3D printed metal augment, and customized triflange cup could achieve satisfactory clinical outcomes.

摘要

分析全髋关节置换术(THA)后髋臼骨缺损髋关节翻修的三种重建技术及中期临床疗效。这是一项回顾性病例系列研究。纳入研究的109例患者(109髋)均为2015年1月至2021年12月在中国人民解放军总医院第四医学中心骨科高级病房及中国人民解放军总医院第一医学中心骨科行髋关节翻修术治疗髋臼骨缺损的患者。根据术前模拟手术及不同的骨缺损重建技术,患者分别分为普通髋臼杯组、植骨组或三翼杯组。普通髋臼杯组54例患者(54髋),采用非骨水泥多孔金属髋臼杯(包括超大号髋臼杯)重建,其中男性23例,女性31例,年龄(59.6±9.9)岁(范围:32至76岁);植骨组44例患者(44髋),采用个体化三维(3D)打印多孔金属垫块及非骨水泥多孔金属髋臼杯重建,其中男性18例,女性26例,年龄(52.8±13.6)岁(范围:17至76岁);三翼杯组11例患者(11髋),采用个体化3D打印多孔金属三翼杯重建,其中男性5例,女性6例,年龄(59.4±11.2)岁(范围:43至78岁)。于术后3、6、12个月及此后每年门诊评估影像学结果,包括旋转中心高度、旋转中心偏移及肢体长度差异(LLD),以及临床结果,包括Harris髋关节评分(HHS)和视觉模拟评分(VAS)。最后一次随访于2024年3月完成,并比较最后一次随访及术前的所有参数。采用配对样本检验和重复测量方差分析对手术前后的影像学和临床参数进行分析。所有THA后髋臼骨缺损患者的髋关节翻修术均已完成并随访超过两年。普通髋臼杯组随访时间为(6.5±1.7)年(范围:2.8至9.3年),植骨组为(6.0±1.3)年(范围:3.5至9.0年)。三翼杯组随访时间为(2.8±0.6)年(范围:2.0至3.8年)。在最后一次随访时,普通髋臼杯组54髋的旋转中心高度、旋转中心偏移及LLD分别为(24.2±5.6)mm、(29.1±5.5)mm及(4.6±3.3)mm,旋转中心高度和LLD均显著低于术前髋关节( =9.671,<0.01; =6.073,<0.01)。在植骨组,44髋的旋转中心高度、旋转中心偏移及LLD分别为(22.4±9.0)mm、(25.4±5.5)mm及(6.0±4.0)mm,均显著低于术前髋关节( =9.071,<0.01; =11.345,<0.01; =4.927,<0.01)。在三翼杯组,11髋的旋转中心高度、旋转中心偏移及LLD分别为(22.7±6.0)mm、(30.9±8.0)mm及(5.3±2.2)mm,旋转中心高度和LLD均显著低于术前髋关节( =2.716, =0.022; =6.226,<0.01)。在最后一次随访时,普通髋臼杯组有3例患者发生骨折,1例患者发生脱位,分别在麻醉下行骨折复位及闭合复位。在植骨组,1例患者发生脱位,在麻醉下行切开复位。三组患者术后HHS和VAS均显著改善,差异有统计学意义(均<0.01)。三翼杯组无并发症发生。最后一次随访时的X线检查显示所有假体及垫块位置稳定,未观察到松动或移位。对于THA后髋臼骨缺损行髋关节翻修的患者,术前手术模拟及预演有助于外科医生选择简便有效的重建技术。针对性选择超大号髋臼杯、个体化3D打印金属垫块及定制三翼杯可取得满意的临床疗效。

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