Scientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Bull Exp Biol Med. 2024 Jun;177(2):274-277. doi: 10.1007/s10517-024-06172-2. Epub 2024 Aug 1.
We performed a matched-pair analysis of the content of GDF11 and GDF15 proteins in the plasma of patients (56 middle-aged men) with obstructive sleep apnea syndrome (OSAS) and healthy volunteers (27 men with no complaints of sleep disorders). The groups were comparable in terms of age and presence of chronic diseases. No statistically significant differences in GDF11 content in the studied groups were revealed, while the content of GDF15 in the OSAS group was 1.3 times higher. These results require further research from the viewpoint of geriatric somnology and molecular biology.
我们对患有阻塞性睡眠呼吸暂停综合征（OSAS）的患者（56 名中年男性）和健康志愿者（27 名无睡眠障碍抱怨的男性）的血浆中 GDF11 和 GDF15 蛋白含量进行了配对分析。两组在年龄和慢性病方面具有可比性。研究组之间的 GDF11 含量没有统计学上的显著差异，而 OSAS 组的 GDF15 含量则高出 1.3 倍。这些结果需要从老年睡眠医学和分子生物学的角度进一步研究。
