School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200135, China.
Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
BMC Endocr Disord. 2024 Aug 2;24(1):136. doi: 10.1186/s12902-024-01625-1.
The prevalence of obesity is escalating. Previous research has concentrated on the link between frailty and obesity; however, the association between prefrailty and obesity has been less studied. Prefrailty screening and intervention may prevent or postpone frailty in older persons.
The study was to investigate into the relationship between prefrailty and several obesity indicators in Chinese community-dwelling older individuals.
This research employed the Frailty Screening Index to investigate the frailty phenotype of people living in Shanghai. Bioelectrical impedance analysis was used for evaluating body composition.
There were 510 participants (39.0%) with high visceral adipose areas. Participants with a high visceral adipose area showed a higher risk of prefrailty (adjusted OR, 1.53; 95% CI, 1.19-1.96), according to multivariate models. When body mass index (BMI) and visceral fat area (VFA) were combined, it was discovered that having an overweight BMI with normal VFA was a protective factor for prefrailty (corrected OR, 0.62; 95% CI, 0.43-0.90), but having a normal weight but excess VFA increased the risk of prefrailty (corrected OR, 1.87; 95% CI, 1.15-3.03).
Visceral fat obesity is an independent risk factor for prefrailty in Chinese older adults. Implementing targeted interventions, such as dietary modifications, increased physical activity, and other lifestyle changes, could play a crucial role in reducing the risk of prefrailty and improving overall health outcomes in this population.
肥胖的流行率正在不断上升。先前的研究主要集中在衰弱与肥胖之间的关系上;然而,衰弱前期与肥胖之间的关联研究较少。衰弱前期的筛查和干预可能预防或延缓老年人的衰弱。
本研究旨在探讨中国社区居住的老年人衰弱前期与几种肥胖指标之间的关系。
本研究采用衰弱筛查指数(Frailty Screening Index)来调查上海居民的衰弱表型。生物电阻抗分析(Bioelectrical impedance analysis)用于评估身体成分。
共有 510 名参与者(39.0%)存在高内脏脂肪面积。根据多变量模型,高内脏脂肪面积的参与者衰弱前期的风险更高(调整后的 OR,1.53;95%CI,1.19-1.96)。当体重指数(BMI)和内脏脂肪面积(VFA)结合时,发现超重 BMI 但正常 VFA 是衰弱前期的保护因素(校正后的 OR,0.62;95%CI,0.43-0.90),但正常体重但内脏脂肪面积过多则增加了衰弱前期的风险(校正后的 OR,1.87;95%CI,1.15-3.03)。
内脏脂肪肥胖是中国老年人衰弱前期的一个独立危险因素。实施有针对性的干预措施,如饮食改变、增加身体活动和其他生活方式改变,可以在降低衰弱前期风险和改善该人群整体健康结果方面发挥关键作用。