National Institute of Standards and Technology, Gaithersburg, MD, USA.
Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Forensic Sci Int Genet. 2024 Jan;68:102946. doi: 10.1016/j.fsigen.2023.102946. Epub 2023 Oct 18.
The DNA Commission of the International Society for Forensic Genetics (ISFG) has developed a set of nomenclature recommendations for short tandem repeat (STR) sequences. These recommendations follow the 2016 considerations of the DNA Commission of the ISFG, incorporating the knowledge gained through research and population studies in the intervening years. While maintaining a focus on backward compatibility with the CE data that currently populate national DNA databases, this report also looks to the future with the establishment of recommended minimum sequence reporting ranges to facilitate interlaboratory comparisons, automated solutions for sequence-based allele designations, a suite of resources to support bioinformatic development, guidance for characterizing new STR loci, and considerations for incorporating STR sequences and other new markers into investigative databases.
国际法庭科学遗传学学会（ISFG）的 DNA 委员会制定了一套短串联重复（STR）序列命名法建议。这些建议遵循了 ISFG DNA 委员会 2016 年的考虑，纳入了这些年来通过研究和人群研究获得的知识。本报告在注重与目前充斥国家 DNA 数据库的 CE 数据向后兼容的同时，还着眼于未来，建立了推荐的最小序列报告范围，以促进实验室间的比较、基于序列的等位基因指定的自动化解决方案、一套支持生物信息学开发的资源、新 STR 基因座特征描述的指导以及将 STR 序列和其他新标记纳入调查数据库的考虑。
