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国际法医遗传学协会(ISFG)DNA委员会:法医分析中Y染色体短串联重复序列(Y-STRs)应用建议的更新

DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis.

作者信息

Gusmão L, Butler J M, Carracedo A, Gill P, Kayser M, Mayr W R, Morling N, Prinz M, Roewer L, Tyler-Smith C, Schneider P M

机构信息

IPATIMUP, Porto, Portugal.

出版信息

Int J Legal Med. 2006 Jul;120(4):191-200. doi: 10.1007/s00414-005-0026-1.

Abstract

The DNA Commission of the International Society of Forensic Genetics (ISFG) regularly publishes guidelines and recommendations concerning the application of DNA polymorphisms to the problems of human identification. A previous recommendation published in 2001 has already addressed Y-chromosome polymorphisms, with particular emphasis on short tandem repeats (STRs). Since then, the use of Y-STRs has become very popular, and numerous new loci have been introduced. The current recommendations address important aspects to clarify problems regarding the nomenclature, the definition of loci and alleles, population genetics and reporting methods

摘要

国际法医遗传学协会(ISFG)DNA委员会定期发布有关DNA多态性在人类身份鉴定问题上应用的指南和建议。2001年发布的一项先前建议已经涉及Y染色体多态性,特别强调短串联重复序列(STR)。从那时起,Y-STR的使用变得非常普遍,并且引入了许多新的基因座。当前的建议涉及重要方面,以澄清有关命名法、基因座和等位基因的定义、群体遗传学和报告方法的问题。

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