Klimas R, Bennett B, Gardner W A
Prostate. 1985;7(1):91-6. doi: 10.1002/pros.2990070110.
Prostatic calculi are rare in children, infrequent below age 40, and common in males over 50. They may be solitary but usually occur in clusters and are associated with some other disease process (nodular hyperplasia, prostatic carcinoma, metabolic abnormalities). They are most often asymptomatic; however, symptoms that may be attributable to prostatic calculi include reduction of the urinary stream, prostatism, and intense lower back and leg pain. Treatment may be accomplished by transurethral resection, but prostatectomy is the best means to insure complete removal. Prostatic calculi may form by two related mechanisms with obstruction and stasis of prostatic fluid as central entities in both. These mechanisms are calcification of corpora amylacea and simple precipitation of prostatic secretion. They may arise spontaneously, initiating an inflammatory reaction that contributes to their growth, or they may arise as the consequence of another pathologic situation producing acinar obstruction. It appears that infection probably occurs secondary to stone formation.
前列腺结石在儿童中罕见，40岁以下不常见，在50岁以上男性中常见。它们可能是单个的，但通常成簇出现，并与其他一些疾病过程（结节性增生、前列腺癌、代谢异常）相关。它们最常无症状；然而，可能归因于前列腺结石的症状包括尿流减少、前列腺增生以及严重的下背部和腿部疼痛。治疗可通过经尿道切除术完成，但前列腺切除术是确保完全切除的最佳方法。前列腺结石可能通过两种相关机制形成，这两种机制都以前列腺液的梗阻和淤滞为核心。这些机制是淀粉样体的钙化和前列腺分泌物的简单沉淀。它们可能自发出现，引发有助于其生长的炎症反应，或者可能作为另一种导致腺泡梗阻的病理情况的结果出现。似乎感染可能继发于结石形成。
