Wang Yaqi, Wang Siyuan, Liu Xinjing, Hu Jiwei, Ma Jie
Department of Breast Surgery, Tangshan People's Hospital, Tangshan, Hebei 063001, P.R. China.
Department of Clinical Medicine, The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510000, P.R. China.
Exp Ther Med. 2024 Jul 16;28(3):366. doi: 10.3892/etm.2024.12655. eCollection 2024 Sep.
The present study was driven by the scarcity of suitable materials for mending partial breast defects and the imperative considerations of safety and durability. The current study presents findings from two female patients, aged 59 and 40, who underwent breast cancer treatment. Patient 1 underwent a mastectomy with a sentinel lymph node biopsy, while patient 2 underwent a partial mastectomy with axillary lymph node dissection. Core needle biopsy confirmed invasive ductal carcinoma in both cases. Breast ultrasound revealed hypoechoic lesions with smooth edges. The reconstruction of the breast defect employed an acellular dermal matrix, and the safety and cosmetic outcomes for each patient were analyzed. At 3 months post-radiotherapy, neither patient experienced significant complications. The preservation of breast contour and volume was satisfactory, with no postoperative tumor recurrences detected. In summary, utilizing an acellular dermal matrix with a three-dimensional grid design for partial breast defect reconstruction offers a viable alternative that aligns with oncological safety standards and provides good cosmetic results.
本研究的开展是由于修补部分乳房缺损的合适材料稀缺，以及对安全性和耐用性的迫切考量。当前研究呈现了两名分别为59岁和40岁的女性乳腺癌患者的研究结果。患者1接受了乳房切除术并进行了前哨淋巴结活检，而患者2接受了部分乳房切除术并进行了腋窝淋巴结清扫。粗针活检证实两例均为浸润性导管癌。乳房超声显示边缘光滑的低回声病变。乳房缺损的重建采用了脱细胞真皮基质，并分析了每位患者的安全性和美容效果。放疗后3个月，两名患者均未出现严重并发症。乳房轮廓和体积的保留情况令人满意，未检测到术后肿瘤复发。总之，使用具有三维网格设计的脱细胞真皮基质进行部分乳房缺损重建提供了一种可行的替代方案，符合肿瘤学安全标准，并能提供良好的美容效果。
