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一例母亲目前感染新冠病毒的新生儿患克-特综合征的病例报告。

A case report of newborn with Klippel-Trenaunay syndrome from mother currently infected by COVID-19.

作者信息

de Godoy Ana Carolina Pereira, de Godoy Jose Maria Pereira, Bestetti Reinaldo Bugarelli

机构信息

Pediatric Intensive Unit Care, Hospital Children and Maternity associated Medicine School of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Brazil.

Cardiology and Cardiovascular Surgery Department of the Medicine School of São José do Rio Preto (FAMERP), CNPq (National Council for Research and Development), Brasilia, Brazil.

出版信息

AME Case Rep. 2024 Jul 10;8:74. doi: 10.21037/acr-23-193. eCollection 2024.

DOI:10.21037/acr-23-193
PMID:39091540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11292084/
Abstract

BACKGROUND

Coronavirus disease 2019 (COVID-19) novel severe acute respiratory syndrome affected the world population with an infectious condition for which therapeutic forms are limited and vascular sequelae are major challenges. Pregnant women are physiologically immunocompromised and can be more affected by the pandemic than the general population. Extra precaution measures against COVID-19 during and after the outbreak are essential to ensure the safety of the newborn. The aim of the present study was to report the cesarean birth of a female child with Klippel-Trenaunay of a mother currently infected by COVID-19.

CASE DESCRIPTION

A newborn of a 21-year-old mother with COVID-19 in the final stage of the disease was born through a cesarean section at full term. The physical examination at birth revealed substantial edema of the left lower limb associated with port-wine stains on the limb and left torso. The ultrasound revealed venous-lymphatic malformation affecting the entire left lower limb, suprapubic region and ipsilateral abdominal region. Two evaluations for COVID-19 were performed and both were negative. Infants of mothers with active COVID-19 infection during the birth period have a low probability of being positive for the disease, but precautions should be taken.

CONCLUSIONS

The association with malformations, such as the rare Klippel-Trenaunay syndrome (KTS), constitutes another challenge regarding the diagnosis and proper conduct to be taken with these children.

摘要

背景

2019年冠状病毒病(COVID-19)这种新型严重急性呼吸综合征以一种感染性疾病影响了全球人口,其治疗方式有限,血管后遗症是主要挑战。孕妇在生理上免疫功能低下,可能比普通人群更容易受到疫情影响。在疫情爆发期间及之后针对COVID-19采取额外的预防措施对于确保新生儿安全至关重要。本研究的目的是报告一名患有Klippel-Trenaunay综合征的女婴通过剖宫产出生,其母亲目前感染了COVID-19。

病例描述

一名21岁患有处于疾病末期的COVID-19的母亲的新生儿足月通过剖宫产出生。出生时的体格检查发现左下肢有大量水肿,伴有该肢体及左躯干的葡萄酒色斑。超声检查显示静脉-淋巴管畸形累及整个左下肢、耻骨上区域和同侧腹部区域。进行了两次COVID-19检测,结果均为阴性。在分娩期间母亲患有活动性COVID-19感染的婴儿感染该疾病呈阳性的可能性较低,但仍应采取预防措施。

结论

与畸形(如罕见的Klippel-Trenaunay综合征(KTS))的关联构成了对这些儿童进行诊断和适当处理的另一项挑战。

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