Steinberg H, Sykes E A
Pharmacol Biochem Behav. 1985 Nov;23(5):857-62. doi: 10.1016/0091-3057(85)90083-8.
The first symposium on endorphins and behavioural processes in Britain was held by the British Psychological Society in March 1985. Against a background of the explosive history of the discovery of endogenous opioids, problems of terminology, and basic mechanisms and concepts, five papers reflect the main fields in which outstanding progress has been made: analgesia, feeding, reward mechanisms, social behaviour and aggression, and addiction. A review of the literature on endorphins and exercise stresses both the value and limitations of trying to unravel a fashionable subject. Endorphin research is multi-disciplinary and highly complex, with tricky technical and conceptual problems and inevitable lack of consensus. Investigators should be more aware of the crucial role that outcomes of behaviour experiments play in the attribution of function to opioid systems.
1985年3月,英国心理学会举办了英国首届内啡肽与行为过程研讨会。以内源性阿片类物质发现的爆炸性历史、术语问题以及基本机制和概念为背景,五篇论文反映了取得显著进展的主要领域:镇痛、进食、奖赏机制、社会行为与攻击行为以及成瘾。一篇关于内啡肽与运动的文献综述强调了试图剖析一个热门主题的价值和局限性。内啡肽研究是多学科且高度复杂的,存在棘手的技术和概念问题,并且不可避免地缺乏共识。研究人员应该更加意识到行为实验结果在将功能归因于阿片系统中所起的关键作用。