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睾丸绒毛膜癌伴盆腔和肺转移:一例报告

Testicular choriocarcinoma with pelvic and pulmonary metastases: a case report.

作者信息

Bai Xin, Liu Xiao H, Liang Hai W, Li Yi S, Shan Biao F, Tang Jian M

机构信息

The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.

Department of Radiation Oncology, The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China.

出版信息

Front Oncol. 2024 Jul 18;14:1427341. doi: 10.3389/fonc.2024.1427341. eCollection 2024.

DOI:10.3389/fonc.2024.1427341
PMID:39091914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11291199/
Abstract

Testicular tumors represent a common form of solid tumor in young men, with choriocarcinoma of the testis being a rare, non-granulomatous germ cell tumor. It accounts for less than 0.3% of all testicular germ cell tumors. Pelvic and pulmonary metastases originating from testicular choriocarcinoma are exceptionally uncommon in men. This study describes a case of a 27-year-old male diagnosed with testicular choriocarcinoma, presenting initially with nausea, vomiting, and abdominal pain. Furthermore, this review encompasses cases of testiclar choriocarcinoma in individuals aged 30 years and below, both in China and internationally, over the past 20 years.

摘要

睾丸肿瘤是年轻男性常见的实体瘤形式,睾丸绒毛膜癌是一种罕见的、非肉芽肿性生殖细胞肿瘤。它占所有睾丸生殖细胞肿瘤的比例不到0.3%。起源于睾丸绒毛膜癌的盆腔和肺转移在男性中极为罕见。本研究描述了一例27岁男性被诊断为睾丸绒毛膜癌的病例,最初表现为恶心、呕吐和腹痛。此外,本综述涵盖了过去20年中国和国际上30岁及以下个体的睾丸绒毛膜癌病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/1ba5f14b9060/fonc-14-1427341-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/378ee0b5d5b1/fonc-14-1427341-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/0dbef8933191/fonc-14-1427341-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/1ba5f14b9060/fonc-14-1427341-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/378ee0b5d5b1/fonc-14-1427341-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/0dbef8933191/fonc-14-1427341-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e4/11291199/1ba5f14b9060/fonc-14-1427341-g003.jpg

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本文引用的文献

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Asian J Surg. 2023 Nov;46(11):5289-5290. doi: 10.1016/j.asjsur.2023.07.070. Epub 2023 Jul 19.
2
Gastrointestinal bleeding caused by metastatic testicular choriocarcinoma: a case report and literature review.转移性睾丸绒毛膜癌致胃肠道出血 1 例报告并文献复习
World J Surg Oncol. 2022 Jun 16;20(1):205. doi: 10.1186/s12957-022-02670-7.
3
Inhibition of TRIM32 by ibr-7 treatment sensitizes pancreatic cancer cells to gemcitabine via mTOR/p70S6K pathway.
IBR-7 处理抑制 TRIM32 通过 mTOR/p70S6K 通路增强胰腺癌细胞对吉西他滨的敏感性。
J Cell Mol Med. 2022 Jan;26(2):515-526. doi: 10.1111/jcmm.17109. Epub 2021 Dec 17.
4
A 20-Year-Old-Man With New Onset of Melena.一名20岁新发黑便的男性。
Gastroenterology. 2022 Jan;162(1):e14-e15. doi: 10.1053/j.gastro.2021.05.065. Epub 2021 Jun 17.
5
Genital exam, a missed piece of the puzzle in medical diagnosis, can be lifesaving in men: A lesson from a case of a state of shock due to duodenal metastasis of testicular choriocarcinoma.生殖器检查,医学诊断中被遗漏的一环,对男性而言可能挽救生命:来自一例睾丸绒毛膜癌十二指肠转移导致休克病例的教训。
Qatar Med J. 2020 Nov 9;2020(2):31. doi: 10.5339/qmj.2020.31. eCollection 2020.
6
Metastatic Testicular Choriocarcinoma: An Unusual Cause of Upper Gastrointestinal Bleed.转移性睾丸绒毛膜癌:上消化道出血的罕见病因
Cureus. 2019 Jul 26;11(7):e5243. doi: 10.7759/cureus.5243.
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Germ cell cancer presenting as gastrointestinal bleeding and developing brain metastases: case report and review of the literature.以胃肠道出血为表现并发生脑转移的生殖细胞癌:病例报告及文献复习。
Future Oncol. 2012 Nov;8(11):1487-93. doi: 10.2217/fon.12.133.
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A case of gastrointestinal bleeding due to duodenal metastasis from a testicular choriocarcinoma.一例因睾丸绒毛膜癌十二指肠转移导致的胃肠道出血。
J Gastrointest Cancer. 2013 Jun;44(2):234-7. doi: 10.1007/s12029-012-9433-y.
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Upper gastrointestinal bleeding as an initial manifestation of metastasis, secondary to a choriocarcinoma in a patient suffering from testicular mixed cell tumour.上消化道出血作为转移的初始表现,继发于一名患有睾丸混合细胞瘤的患者的绒毛膜癌。
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