Department of Ophthalmology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Harbin Purui Eye Hospital, Harbin, China.
Hum Cell. 2024 Sep;37(5):1336-1346. doi: 10.1007/s13577-024-01111-9. Epub 2024 Aug 2.
Carbon quantum dots (CQDs), an emerging nanomaterial, are gaining attention in ophthalmological applications due to their distinctive physical, chemical, and biological characteristics. For example, their inherent fluorescent capabilities offer a novel and promising alternative to conventional fluorescent dyes for ocular disease diagnostics. Furthermore, because of the excellent biocompatibility and minimal cytotoxicity, CQDs are well-suited for therapeutic applications. In addition, functionalized CQDs can effectively deliver drugs to the posterior part of the eyeball to inhibit neovascularization. This review details the use of CQDs in the management of ophthalmic diseases, including various retinal diseases, and ocular infections. While still in its initial phases within ophthalmology, the significant potential of CQDs for diagnosing and treating eye conditions is evident.
碳量子点(CQDs)作为一种新兴的纳米材料,由于其独特的物理、化学和生物学特性,在眼科应用中受到关注。例如,它们固有的荧光特性为眼部疾病诊断提供了一种新颖而有前途的替代传统荧光染料的方法。此外,由于CQDs 的极好的生物相容性和最小的细胞毒性,它们非常适合治疗应用。此外,功能化的 CQDs 可以有效地将药物递送到眼球的后段,以抑制新生血管形成。本综述详细介绍了 CQDs 在眼部疾病管理中的应用,包括各种视网膜疾病和眼部感染。虽然在眼科领域仍处于初期阶段,但 CQDs 在诊断和治疗眼部疾病方面的巨大潜力是显而易见的。