Institute of Nuclear Physics, Polish Academy of Sciences, Radzikowskiego 152, Kraków, 31-342, Poland.
Nature Education Centre of the Jagiellonian University, Gronostajowa 5, Kraków, 30-387, Poland.
Bull Environ Contam Toxicol. 2024 Aug 2;113(2):20. doi: 10.1007/s00128-024-03933-7.
The primary objective of the presented research was to assess the impact of intense global economic development, over the last 100 years, on the bioaccumulation of heavy metals in the human body. This evaluation was conducted based on the measurement of heavy metals in human hair samples collected 100 years ago in present-day southern Poland.In this study, concentrations of lead (Pb), cadmium (Cd), arsenic (As), zinc (Zn), copper (Cu), iron (Fe), and selenium (Se) were measured in 61 hair samples,28 of which were obtained from individuals who lived 100 years ago, while the remaining 33 constituted the contemporary control group. The concentrations were determined using a triple quadrupole inductively coupled plasma mass spectrometer (Agilent 8900). Statistical analysis of the obtained results was conducted using the Principal Cmponent Analysis and the non-parametric Mann-Whitney test. In the case of As, Pb, Cd, and Fe, the concentrations were significantly higher in individuals who lived 100 years ago compared to those living today. Over this period, the median concentrations were shown to have decreased by 95%, 94%, 85%, and 69% for As, Pb, Cd, and Fe, respectively. No statistically significant differences were observed for Cu, Zn, and Se. The results obtained for Pb, Cd, As, and Fe unequivocally indicate that the population studied from 100 years ago was more exposed to internal contamination with these metals than people who live nowadays.
本研究的主要目的是评估过去 100 年中全球经济的快速发展对人体中重金属生物累积的影响。本研究通过测量现今波兰南部地区 100 年前采集的人类头发样本中的重金属来进行评估。在本研究中，使用三重四极杆电感耦合等离子体质谱仪（Agilent 8900）测量了 61 个头发样本中的铅（Pb）、镉（Cd）、砷（As）、锌（Zn）、铜（Cu）、铁（Fe）和硒（Se）的浓度。其中 28 个样本来自 100 年前的个体，而其余 33 个样本则构成了当代对照组。对获得的结果进行了主成分分析和非参数曼-惠特尼检验的统计分析。对于 As、Pb、Cd 和 Fe，100 年前个体的浓度明显高于当今个体。在此期间，As、Pb、Cd 和 Fe 的中位数浓度分别降低了 95%、94%、85%和 69%。Cu、Zn 和 Se 没有观察到统计学上的显著差异。对于 Pb、Cd、As 和 Fe 的结果表明，与当今人群相比，100 年前研究人群受到这些金属内部污染的程度更高。
