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[根据ABO血型匹配选择器官接受者。理论与实践]

[The selection of organ recipients according to the ABO blood group match. Theory and practice].

作者信息

Speiser P

出版信息

Wien Klin Wochenschr. 1985 Nov 22;97(22):848-50.

PMID:3909652
Abstract

The AB0 distribution of the population of Vienna is compared with HLA A, B, C, DR typed transplanted patients (n = 780), kidney donors and potential recipients on the waiting list. The significant differences of AB0 distribution is caused by using group 0 kidney donors for non-0 recipients and donors of groups 0, A and B for group AB recipients. This procedure minimizes the chance of group 0 patients to receive transplants and should be kept in mind by the selection of DR compatible recipients. It is also known that group 0 grafts can develop immune anti A or anti B to the (non-group 0) host, resulting in destruction of the recipient's red cells. The development of such acquired haemolytic anaemia occurs with cyclosporin A medication for immunosuppression.

摘要

将维也纳人群的AB0血型分布与HLA A、B、C、DR分型的移植患者(n = 780)、肾脏供体以及等待名单上的潜在受体进行比较。AB0血型分布的显著差异是由于将0型肾脏供体用于非0型受体,以及将0型、A型和B型供体用于AB型受体所致。此程序将0型患者接受移植的机会降至最低,在选择DR配型的受体时应予以考虑。还已知0型移植物可对(非0型)宿主产生免疫性抗A或抗B,导致受体红细胞破坏。这种获得性溶血性贫血的发生与用于免疫抑制的环孢素A药物有关。

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