The First Affiliated Hospital of Xinxiang Medical University, Henan 453003, China.
Department of Psychology, Xinxiang Medical University, Henan 453003, China; Mental Illness and Cognitive Neuroscience Key Laboratory of Xinxiang (Xinxiang Medical University), Xinxiang 453003, Henan Province, China.
Conscious Cogn. 2024 Sep;124:103734. doi: 10.1016/j.concog.2024.103734. Epub 2024 Aug 3.
The cognitive neural mechanisms by which sleep deprivation affects cognitive flexibility are poorly understood. Therefore, the study investigated the neuroelectrophysiological basis of the effect of 24 h sleep deprivation on cognitive flexibility in adolescents. 72 participants (36 females, mean age ± SD=20.46 ± 2.385 years old) participated in the study and were randomly assigned to the sleep deprivation group and control group. They were instructed to complete a task switch paradigm, during which participants' behavioral and electroencephalographic data were recorded. Behaviorally, there were significant between-group differences in accuracy. The results of event-related potential showed that the P2, N2 and P3 components had significant group effects or interaction effects. At the time-frequency level, there were statistically significant differences between the delta and theta bands. These results suggested that 24 h sleep deprivation affected problem-solving effectiveness rather than efficiency, mainly because it systematically impaired cognitive processing associated with cognitive flexibility.
睡眠剥夺影响认知灵活性的神经认知机制尚不清楚。因此，本研究调查了 24 小时睡眠剥夺对青少年认知灵活性的神经电生理基础。72 名参与者（36 名女性，平均年龄±标准差=20.46±2.385 岁）参与了这项研究，并被随机分配到睡眠剥夺组和对照组。他们被要求完成一项任务转换范式，在此期间记录参与者的行为和脑电图数据。行为上，准确性存在显著的组间差异。事件相关电位的结果表明，P2、N2 和 P3 成分具有显著的组间效应或交互效应。在时频水平上，δ和θ频段之间存在统计学上的显著差异。这些结果表明，24 小时睡眠剥夺影响了解决问题的效果，而不是效率，主要是因为它系统地损害了与认知灵活性相关的认知加工。
