Center for Geriatric Medicine, University Clinic Heidelberg, AGAPLESION Bethanien Krankenhaus Heidelberg, Rohrbacher Straße 149, 69126 Heidelberg, Germany.
The Royal Marsden NHS Foundation Trust, London, UK.
Eur J Cancer. 2024 Sep;209:114237. doi: 10.1016/j.ejca.2024.114237. Epub 2024 Jul 22.
As the global population ages, so does the number of older people being diagnosed, treated and surviving cancer. Challenges to providing appropriate healthcare management stem from the heterogeneity common in this population. Although malnutrition is highly prevalent in older people with cancer, ranging between 30 % and 80 % according to some analyses, is associated with frailty, and has been shown to be a major risk factor for poor treatment response and worse overall survival, addressing nutrition status is not always a priority among oncology healthcare providers. Evaluation of nutritional status is a two-step process: screening identifies risk factors for reduced nutritional intake and deficits that require more in-depth assessment. Screening activities can be as simple as taking weight and BMI measurements or using short nutritional questionnaires and asking the patient about unintentional weight loss to identify potential nutritional risk. Using geriatric assessment, deficits in the nutritional domain as well as in others reveal potentially reversible geriatric and medical problems to guide specific therapeutic interventions. The authors of this paper are experts in the fields of geriatric medicine, oncology, and nutrition science and believe that there is not only substantial evidence to support regularly performing screening and assessment of nutritional status in older patients with cancer, but that these measures lead to the planning and implementation of patient-centered approaches to nutrition management and thus enhanced geriatric-oncology care. This paper presents rationale for systematic nutrition screening and assessment in older adults with cancer.
随着全球人口老龄化,被诊断、治疗和幸存癌症的老年人数量也在增加。为这一人群提供适当医疗保健管理的挑战源于其常见的异质性。尽管癌症老年患者的营养不良非常普遍,根据一些分析,其比例在 30%至 80%之间,与虚弱有关,并已被证明是治疗反应不佳和总体生存率下降的主要危险因素,但营养状况的评估并不总是肿瘤学医疗保健提供者的优先事项。营养状况评估是一个两步过程:筛查确定了营养摄入减少和需要更深入评估的缺陷的风险因素。筛查活动可以很简单,例如测量体重和 BMI,或使用简短的营养问卷,并询问患者是否有无意的体重减轻,以确定潜在的营养风险。使用老年评估,可以揭示营养领域以及其他领域的缺陷,从而发现潜在可逆转的老年和医学问题,以指导特定的治疗干预措施。本文的作者是老年医学、肿瘤学和营养科学领域的专家,他们认为,不仅有大量证据支持定期对癌症老年患者进行营养筛查和评估,而且这些措施还可以制定以患者为中心的营养管理方法,并因此加强老年肿瘤学护理。本文提出了对癌症老年患者进行系统营养筛查和评估的基本原理。