Department of Geriatric Respiratory, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Guangdong Provincial Geriatrics Institute, Southern Medical University, No. 106, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Department of Respiratory, Zhongshan City People's Hospital, Zhongshan, 528400, Guangdong, China.
Sci Rep. 2024 Aug 3;14(1):18003. doi: 10.1038/s41598-024-69142-8.
Lung cancer is intricately associated with genetic susceptibility, leading to familial clustering among affected individuals. This cross-sectional study aimed to assess the knowledge, attitude, and practice (KAP) toward lung cancer risk among the offspring of lung cancer patients. This study was conducted at Guangdong Provincial People's Hospital between April 2023 and August 2023. Participants' demographic characteristics and KAP toward lung cancer risk were collected through questionnaires. A total of 481 valid questionnaires were enrolled, with 243 (50.52%) males, and 242 (50.31%) aged > 40 years old. The mean scores for knowledge, attitude, and practice were 8.54 ± 2.60 (range: 0-13), 25.93 ± 3.16 (range: 7-35), and 17.47 ± 4.30 (range: 5-25), respectively. Structural equation modeling indicated that knowledge exerted a negative direct effect on attitude (β = - 0.417, P = 0.006) but a positive direct effect on practice (β = 0.733, P = 0.025). Additionally, attitudes displayed a negative direct effect on practice (β = - 1.707, P = 0.002). In conclusion, offspring of lung cancer patients exhibited insufficient knowledge, positive attitude, and suboptimal practice toward lung cancer risk.
肺癌与遗传易感性密切相关，导致受影响个体中存在家族聚集现象。本横断面研究旨在评估肺癌患者子女对肺癌风险的知识、态度和实践（KAP）。该研究于 2023 年 4 月至 8 月在广东省人民医院进行。通过问卷调查收集参与者的人口统计学特征和对肺癌风险的 KAP。共纳入 481 份有效问卷，其中男性 243 人（50.52%），年龄>40 岁 242 人（50.31%）。知识、态度和实践的平均得分为 8.54±2.60（范围：0-13）、25.93±3.16（范围：7-35）和 17.47±4.30（范围：5-25）。结构方程模型表明，知识对态度有负向直接影响（β=-0.417，P=0.006），对实践有正向直接影响（β=0.733，P=0.025）。此外，态度对实践有负向直接影响（β=-1.707，P=0.002）。总之，肺癌患者的子女对肺癌风险的知识不足，态度积极，实践欠佳。
