• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

沃尔巴克氏体赋予非洲埃及伊蚊对昆虫病原真菌平沙淡紫拟青霉的抗性。

Wolbachia confers protection against the entomopathogenic fungus Metarhizium pingshaense in African Aedes aegypti.

机构信息

Institut de Recherche en Sciences de la Santé, Direction Régionale de l'Ouest, Dioulasso, Burkina Faso.

Institut National de Santé Publique/Centre Muraz, Dioulasso, Burkina Faso.

出版信息

Environ Microbiol Rep. 2024 Aug;16(4):e13316. doi: 10.1111/1758-2229.13316.

DOI:10.1111/1758-2229.13316
PMID:39097980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11298244/
Abstract

Symbiotic and pathogenic microorganisms such as bacteria and fungi represent promising alternatives to chemical insecticides to respond to the rapid increase of insecticide resistance and vector-borne disease outbreaks. This study investigated the interaction of two strains of Wolbachia, wAlbB and wAu, with the natural entomopathogenic fungi from Burkina Faso Metarhizium pingshaense, known to be lethal against Anopheles mosquitoes. In addition to showing the potential of Metarhizium against African Aedes aegypti wild-type populations, our study shows that the wAlbB and wAu provide a protective advantage against entomopathogenic fungal infections. Compared to controls, fungal-infected wAu and wAlbB-carrying mosquitoes showed higher longevity, without any significant impact on fecundity and fertility phenotypes. This study provides new insights into the complex multipartite interaction among the mosquito host, the Wolbachia endosymbiont and the entomopathogenic fungus that might be employed to control mosquito populations. Future research should investigate the fitness costs of Wolbachia, as well as its spread and prevalence within mosquito populations. Additionally, evaluating the impact of Wolbachia on interventions involving Metarhizium pingshaense through laboratory and semi-field population studies will provide valuable insights into the effectiveness of this combined approach.

摘要

共生和病原微生物，如细菌和真菌，是应对杀虫剂抗性快速增加和媒介传播疾病爆发的有前途的替代品。本研究调查了两种沃尔巴克氏体（wAlbB 和 wAu）与来自布基纳法索的天然昆虫病原真菌绿僵菌的相互作用，已知绿僵菌对疟蚊具有致死作用。除了显示绿僵菌对非洲埃及伊蚊野生型种群的潜在作用外，我们的研究还表明，wAlbB 和 wAu 提供了对昆虫病原真菌感染的保护优势。与对照组相比，感染真菌的携带 wAu 和 wAlbB 的蚊子表现出更高的寿命，而对生育力和繁殖表型没有任何显著影响。本研究为蚊宿主、沃尔巴克氏体共生体和昆虫病原真菌之间复杂的多组分相互作用提供了新的见解，这可能被用于控制蚊子种群。未来的研究应该调查沃尔巴克氏体的适应成本，以及其在蚊子种群中的传播和流行情况。此外，通过实验室和半野外种群研究评估沃尔巴克氏体对涉及绿僵菌的干预措施的影响，将为这种联合方法的有效性提供有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/0ea7c57fbe99/EMI4-16-e13316-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/1270ebb583b9/EMI4-16-e13316-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/82bf56a11cb3/EMI4-16-e13316-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/bed0dd6eee5a/EMI4-16-e13316-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/2ff8c8449bfc/EMI4-16-e13316-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/2152fcf33a66/EMI4-16-e13316-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/0ea7c57fbe99/EMI4-16-e13316-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/1270ebb583b9/EMI4-16-e13316-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/82bf56a11cb3/EMI4-16-e13316-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/bed0dd6eee5a/EMI4-16-e13316-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/2ff8c8449bfc/EMI4-16-e13316-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/2152fcf33a66/EMI4-16-e13316-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3b5/11298244/0ea7c57fbe99/EMI4-16-e13316-g002.jpg

相似文献

1
Wolbachia confers protection against the entomopathogenic fungus Metarhizium pingshaense in African Aedes aegypti.沃尔巴克氏体赋予非洲埃及伊蚊对昆虫病原真菌平沙淡紫拟青霉的抗性。
Environ Microbiol Rep. 2024 Aug;16(4):e13316. doi: 10.1111/1758-2229.13316.
2
Impacts of fungal entomopathogens on survival and immune responses of Aedes albopictus and Culex pipiens mosquitoes in the context of native Wolbachia infections.真菌性昆虫病原体对携带本土沃尔巴克氏体的白纹伊蚊和致倦库蚊存活和免疫反应的影响。
PLoS Negl Trop Dis. 2021 Nov 29;15(11):e0009984. doi: 10.1371/journal.pntd.0009984. eCollection 2021 Nov.
3
Entomopathogenic fungi increases susceptibility to insecticides in highly resistant malaria mosquitoes .昆虫病原真菌会增加高抗性疟蚊对杀虫剂的易感性。
Wellcome Open Res. 2025 Feb 24;9:290. doi: 10.12688/wellcomeopenres.21238.2. eCollection 2024.
4
Lab-scale characterization and semi-field trials of Wolbachia Strain wAlbB in a Taiwan Wolbachia introgressed Ae. aegypti strain.在台湾具有沃尔巴克氏体的埃及伊蚊种群中，沃尔巴克氏体菌株 wAlbB 的实验室规模特征和半田间试验。
PLoS Negl Trop Dis. 2022 Jan 11;16(1):e0010084. doi: 10.1371/journal.pntd.0010084. eCollection 2022 Jan.
5
Native entomopathogenic Metarhizium spp. from Burkina Faso and their virulence against the malaria vector Anopheles coluzzii and non-target insects.来自布基纳法索的本土昆虫病原真菌绿僵菌及其对疟疾传播媒介冈比亚按蚊和非靶标昆虫的毒力。
Parasit Vectors. 2018 Mar 27;11(1):209. doi: 10.1186/s13071-018-2796-6.
6
The combination of the entomopathogenic fungus Metarhizium anisopliae with the insecticide Imidacloprid increases virulence against the dengue vector Aedes aegypti (Diptera: Culicidae).球孢白僵菌与杀虫剂吡虫啉联合使用可提高对登革热传播媒介埃及伊蚊（双翅目：蚊科）的毒力。
Parasit Vectors. 2011 Jan 25;4:8. doi: 10.1186/1756-3305-4-8.
7
Establishment of Wolbachia infection in Aedes aegypti from Pakistan via embryonic microinjection and semi-field evaluation of general fitness of resultant mosquito population.通过胚胎显微注射在巴基斯坦的埃及伊蚊中建立沃尔巴克氏体感染，并对由此产生的蚊子种群的一般适应性进行半田间评估。
Parasit Vectors. 2022 Jun 6;15(1):191. doi: 10.1186/s13071-022-05317-4.
8
Adhesion and virulence properties of native Metarhizium fungal strains from Burkina Faso for the control of malaria vectors.来自布基纳法索的本土金龟子绿僵菌菌株对疟疾传播媒介的控制的黏附性和毒力特性。
Parasit Vectors. 2023 Nov 7;16(1):406. doi: 10.1186/s13071-023-05831-z.
9
Effectiveness of Wolbachia-mediated sterility coupled with sterile insect technique to suppress adult Aedes aegypti populations in Singapore: a synthetic control study.沃尔巴克氏体介导的不育与不育昆虫技术相结合对抑制新加坡埃及伊蚊成虫种群的效果：一项合成对照研究。
Lancet Planet Health. 2024 Sep;8(9):e617-e628. doi: 10.1016/S2542-5196(24)00169-4.
10
Infection of highly insecticide-resistant malaria vector Anopheles coluzzii with entomopathogenic bacteria Chromobacterium violaceum reduces its survival, blood feeding propensity and fecundity.经昆虫病原细菌——彩虹色杆菌感染后，抗药性极强的疟疾传播媒介按蚊（Anopheles coluzzii）的存活率、吸血倾向和繁殖力降低。
Malar J. 2020 Oct 2;19(1):352. doi: 10.1186/s12936-020-03420-4.

引用本文的文献

1
Wolbachia enhances the survival of Drosophila infected with fungal pathogens.沃尔巴克氏体增强感染真菌病原体的果蝇的存活率。
BMC Biol. 2025 Feb 11;23(1):42. doi: 10.1186/s12915-025-02130-0.

本文引用的文献

1
Wolbachia strain wAlbB shows favourable characteristics for dengue control use in Aedes aegypti from Burkina Faso.沃尔巴克氏体菌株 wAlbB 显示出有利于在布基纳法索的埃及伊蚊中控制登革热的特性。
Environ Microbiol. 2024 Mar;26(3):e16588. doi: 10.1111/1462-2920.16588.
2
Differences in proteome perturbations caused by the Wolbachia strain wAu suggest multiple mechanisms of Wolbachia-mediated antiviral activity.由 Wolbachia 菌株 wAu 引起的蛋白质组扰动差异表明 Wolbachia 介导抗病毒活性的多种机制。
Sci Rep. 2023 Jul 20;13(1):11737. doi: 10.1038/s41598-023-38127-4.
3
Spatial Distribution and Long-Term Persistence of -Infected in the Mentari Court, Malaysia.
马来西亚门塔里法院中感染……的空间分布与长期持续性 。（注：原文中“-Infected”部分内容不完整）
Insects. 2023 Apr 11;14(4):373. doi: 10.3390/insects14040373.
4
Association of 410L, 1016I and 1534C kdr mutations with pyrethroid resistance in Aedes aegypti from Ouagadougou, Burkina Faso, and development of a one-step multiplex PCR method for the simultaneous detection of 1534C and 1016I kdr mutations.与布基纳法索瓦加杜古埃及伊蚊对拟除虫菊酯的抗性相关的 410L、1016I 和 1534C kdr 突变，以及一种用于同时检测 1534C 和 1016I kdr 突变的一步多重 PCR 方法的开发。
Parasit Vectors. 2023 Apr 19;16(1):137. doi: 10.1186/s13071-023-05743-y.
5
First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016-2017.首次全面分析西非虫媒病毒疫情期间埃及伊蚊的生态学：2016-2017 年布基纳法索瓦加杜古登革热疫情。
PLoS Negl Trop Dis. 2022 Jul 6;16(7):e0010059. doi: 10.1371/journal.pntd.0010059. eCollection 2022 Jul.
6
Impacts of fungal entomopathogens on survival and immune responses of Aedes albopictus and Culex pipiens mosquitoes in the context of native Wolbachia infections.真菌性昆虫病原体对携带本土沃尔巴克氏体的白纹伊蚊和致倦库蚊存活和免疫反应的影响。
PLoS Negl Trop Dis. 2021 Nov 29;15(11):e0009984. doi: 10.1371/journal.pntd.0009984. eCollection 2021 Nov.
7
High Temperature Cycles Result in Maternal Transmission and Dengue Infection Differences Between Strains in Aedes aegypti.高温周期导致埃及伊蚊中不同株系的母婴传播和登革热感染存在差异。
mBio. 2021 Dec 21;12(6):e0025021. doi: 10.1128/mBio.00250-21. Epub 2021 Nov 9.
8
Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue.沃尔巴克氏体感染蚊子的部署对登革热控制的效果。
N Engl J Med. 2021 Jun 10;384(23):2177-2186. doi: 10.1056/NEJMoa2030243.
9
Dengue Virus Infection and Associated Risk Factors in Africa: A Systematic Review and Meta-Analysis.登革热病毒感染及相关危险因素在非洲：系统评价和荟萃分析。
Viruses. 2021 Mar 24;13(4):536. doi: 10.3390/v13040536.
10
Infertility and fecundity loss of Wolbachia-infected Aedes aegypti hatched from quiescent eggs is expected to alter invasion dynamics.预计受感染的埃及伊蚊从休眠卵中孵化后会导致不孕和生育力丧失，从而改变入侵动态。
PLoS Negl Trop Dis. 2021 Feb 16;15(2):e0009179. doi: 10.1371/journal.pntd.0009179. eCollection 2021 Feb.