Wanjari Dnyanshree, Paul Amreesh, Bhalerao Nikhil, Sawant Urvi
Department of Anaesthesiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Jul 3;16(7):e63726. doi: 10.7759/cureus.63726. eCollection 2024 Jul.
A cancer diagnosis marks the beginning of a difficult path filled with a profound battle against the excruciating pain associated with the illness. Cancer-related pain, which is complex and emotionally distressing, presents unique challenges in terms of treatment. Abdominal cancers and metastases frequently result in severe and unmanageable pain that does not respond well to traditional medications. In such situations, interventions like neurolysis and radiofrequency ablation of the splanchnic nerves and celiac plexus have emerged as effective strategies, providing enhanced pain relief and reducing the need for narcotic painkillers. In this case report, we describe a case of a 38-year-old man with a longstanding history of chronic pancreatitis with a polypoid growth close to the ampulla in the duodenal bulb. The patient was given pain medications to alleviate the pain, but the severe stomach pain, vomiting, and fever persisted. Imaging tests supported the diagnosis and showed chronic pancreatitis, a continuing inflammatory process, and a periampullary adenocarcinoma. The patient had significant pain while being positioned prone for the diagnostic block, hence an erector spinae plane block was done before the radiofrequency ablation. The patient received radiofrequency ablation at the T11 and T12 levels after receiving a diagnostic splanchnic nerve block, significantly reducing pain. The effectiveness of these interventional procedures in enhancing the patient's quality of life and decreasing their dependence on narcotic drugs was highlighted by follow-up visits at two, four, and six months that revealed little to no discomfort. This instance emphasizes the importance of considering neurolysis and radiofrequency ablation as essential alternatives for treating severe abdominal pain brought on by chronic pancreatitis and abdominal cancer.
癌症诊断标志着一段艰难旅程的开始,这是一场与疾病带来的剧痛进行的深刻斗争。与癌症相关的疼痛复杂且令人情绪痛苦,在治疗方面带来了独特挑战。腹部癌症及其转移常常导致严重且难以控制的疼痛,传统药物对此效果不佳。在这种情况下,诸如内脏神经和腹腔丛的神经溶解及射频消融等干预措施已成为有效的治疗策略,能增强疼痛缓解效果并减少对麻醉性止痛药的需求。在本病例报告中,我们描述了一名38岁男性患者,他有长期慢性胰腺炎病史,十二指肠球部靠近壶腹处有一个息肉样肿物。患者接受了止痛药物治疗以缓解疼痛,但严重的胃痛、呕吐和发热仍持续存在。影像学检查支持了诊断,显示为慢性胰腺炎、持续的炎症过程以及壶腹周围腺癌。患者在俯卧位进行诊断性阻滞时疼痛明显,因此在射频消融术前进行了竖脊肌平面阻滞。在接受诊断性内脏神经阻滞后,患者在T11和T12水平接受了射频消融,疼痛显著减轻。在术后2个月、4个月和6个月的随访中发现患者几乎没有不适,这突出了这些介入手术在提高患者生活质量和减少其对麻醉药物依赖方面的有效性。这个病例强调了将神经溶解和射频消融视为治疗慢性胰腺炎和腹部癌症所致严重腹痛的重要替代方法的重要性。