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用于神经内分泌肿瘤特征描述的创新成像方法:联合双能CT与灌注方案的实施

Innovative imaging approaches for neuroendocrine tumor characterization: Combined dual energy CT and perfusion protocol implementation.

作者信息

Madrid Lewis Mariana Sofia, Manjarres Guevara Abel Enrique, Madrid Jaramillo Jaime Alfonso, Campana Granda Carlos Martín

机构信息

Department of Radiology, Centro Especializado En Radiología e Imágenes Diagnosticas (Cerid), Barranquilla, Colombia.

出版信息

Radiol Case Rep. 2024 Jul 20;19(10):4225-4231. doi: 10.1016/j.radcr.2024.06.063. eCollection 2024 Oct.

DOI:10.1016/j.radcr.2024.06.063
PMID:39101023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11295452/
Abstract

The article addresses the diagnostic value of the combined use of computed tomography (CT) perfusion and dual-energy CT (DECT) in patients with neuroendocrine tumors. It emphasizes the heterogeneity and complexity of these neoplasms, primarily affecting the gastrointestinal tract, bronchopulmonary system, and pancreas. While conventional CT is widely employed in their diagnosis, the combination of CT perfusion and dual-energy CT offers greater precision, particularly in detecting synchronous tumors and characterizing their vascularization. A clinical case of a patient with chronic abdominal symptoms, whose diagnosis was facilitated using both combined techniques, is presented. The discussion explores how CT perfusion assesses tumor vascularization and how dual-energy CT improves soft tissue differentiation, resulting in increased diagnostic accuracy. It is highlighted that this approach not only enhances detection rates but also positively impacts clinical management and healthcare costs. Therefore, the importance of considering these advanced tools in the diagnosis of neuroendocrine tumors to improve diagnostic precision and efficiency in patient care is underscored.

摘要

本文探讨了计算机断层扫描(CT)灌注成像与双能CT(DECT)联合应用于神经内分泌肿瘤患者的诊断价值。文中强调了这些肿瘤的异质性和复杂性,主要累及胃肠道、支气管肺系统和胰腺。虽然传统CT在其诊断中广泛应用,但CT灌注成像与双能CT的联合应用能提供更高的精准度,尤其是在检测同步肿瘤及其血管特征方面。本文介绍了一名有慢性腹部症状患者的临床病例,其诊断借助了这两种联合技术。讨论探讨了CT灌注成像如何评估肿瘤血管生成,以及双能CT如何改善软组织分辨能力,从而提高诊断准确性。文中强调,这种方法不仅提高了检测率,还对临床管理和医疗成本产生了积极影响。因此,强调了在神经内分泌肿瘤诊断中考虑这些先进工具对于提高患者护理诊断精准度和效率的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/a581b480590b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/0d1815545ce0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/e235aa91c725/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/a581b480590b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/0d1815545ce0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/e235aa91c725/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3384/11295452/a581b480590b/gr3.jpg

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本文引用的文献

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Pancreatic CT perfusion: quantitative meta-analysis of disease discrimination, protocol development, and effect of CT parameters.胰腺CT灌注:疾病鉴别、方案制定及CT参数影响的定量荟萃分析
Insights Imaging. 2023 Jul 21;14(1):132. doi: 10.1186/s13244-023-01471-0.
2
Diagnostic Management of Gastroenteropancreatic Neuroendocrine Neoplasms: Technique Optimization and Tips and Tricks for Radiologists.胃肠胰神经内分泌肿瘤的诊断管理:放射科医师的技术优化及技巧。
Tomography. 2023 Jan 27;9(1):217-246. doi: 10.3390/tomography9010018.
3
Use of dual-layer spectral detector computed tomography in the diagnosis of pancreatic neuroendocrine neoplasms.
双层光谱探测器计算机断层扫描在胰腺神经内分泌肿瘤诊断中的应用。
Eur J Radiol. 2023 Feb;159:110660. doi: 10.1016/j.ejrad.2022.110660. Epub 2022 Dec 19.
4
Application of spectral CT combined with perfusion scan in diagnosis of pancreatic neuroendocrine tumors.光谱CT联合灌注扫描在胰腺神经内分泌肿瘤诊断中的应用
Insights Imaging. 2022 Sep 4;13(1):145. doi: 10.1186/s13244-022-01282-9.
5
Utility of Quantitative Metrics From Dual-Layer Spectral-Detector CT for Differentiation of Pancreatic Neuroendocrine Tumor and Neuroendocrine Carcinoma.双层光谱探测器 CT 定量指标在胰腺神经内分泌肿瘤和神经内分泌癌鉴别诊断中的应用。
AJR Am J Roentgenol. 2022 Jun;218(6):999-1009. doi: 10.2214/AJR.21.27017. Epub 2022 Jan 19.
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A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer.灌注计算机断层扫描在腹部癌症中作用的系统评价
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