Dodi G, Pirone E, Bettin A, Veller C, Infantino A, Pianon P, Mortellaro L M, Lise M
Br J Surg. 1985 Dec;72(12):967-9. doi: 10.1002/bjs.1800721210.
The perianal mycotic flora was studied in proctological patients with and without pruritus ani, as well as in control subjects. Four groups of patients underwent perianal mycoculture. In Group 1, 53 patients with anal pruritus were treated for benign anorectal disease. In Group 2, 24 patients with no underlying disease presented with anal pruritus. Both of these groups underwent concomitant chemical and parasitical examination of the faeces and an oral glucose tolerance test. In Group 3, 50 patients without pruritus ani at present or in the past were treated for benign anorectal diseases. In Group 4, 47 surgical patients without pruritus ani were treated for benign (9) and malignant (38) non-proctological diseases. In Group 1 the mycoculture was positive in 24/53 patients (Candida albicans 14, dermatophytes 10). In Group 2 fungal infections were seen in 16/24 patients (C. albicans 7, dermatophytes 9). No parasites or diabetes were found in either group. In Group 3 C. albicans was isolated in 14/50 patients. In Group 4 C. albicans was found in 11/47 cases (2 in benign, 9 in malignant diseases). Infection by C. albicans was observed in all groups studied, independent of the presence of disease or anal pruritus. The presence of dermatophytes was always associated with pruritus ani.
对患有和未患有肛门瘙痒症的直肠病患者以及对照受试者的肛周真菌菌群进行了研究。四组患者接受了肛周真菌培养。第1组，53例患有肛门瘙痒症的患者因良性肛肠疾病接受治疗。第2组，24例无基础疾病但出现肛门瘙痒症的患者。这两组患者均同时接受了粪便的化学和寄生虫检查以及口服葡萄糖耐量试验。第3组，50例目前或过去无肛门瘙痒症的患者因良性肛肠疾病接受治疗。第4组，47例无肛门瘙痒症的外科患者因良性（9例）和恶性（38例）非直肠疾病接受治疗。第1组中，24/53例患者真菌培养呈阳性（白色念珠菌14例，皮肤癣菌10例）。第2组中，16/24例患者发现真菌感染（白色念珠菌7例，皮肤癣菌9例）。两组均未发现寄生虫或糖尿病。第3组中，14/50例患者分离出白色念珠菌。第4组中，11/47例病例发现白色念珠菌（良性疾病2例，恶性疾病9例）。在所研究的所有组中均观察到白色念珠菌感染，与疾病或肛门瘙痒症的存在无关。皮肤癣菌的存在总是与肛门瘙痒症相关。
