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破裂性大子宫外孕性葡萄胎:妊娠滋养细胞疾病的一种罕见表现。

Ruptured large ectopic hydatidiform mole: an infrequent presentation of gestational trophoblastic disease.

机构信息

Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), Raipur, 492001, Chhattisgarh, India.

Asha Sonography and Imaging Centre, Nipani, Belgaum, Karnataka, India.

出版信息

J Ultrasound. 2024 Dec;27(4):941-945. doi: 10.1007/s40477-024-00946-0. Epub 2024 Aug 5.

Abstract

Gestational trophoblastic disease (GTD) comprises hydatidiform mole, invasive mole, epithelioid trophoblastic tumor, placental site trophoblastic tumor, and choriocarcinoma. Ectopic molar gestation (EMG) is exceedingly rare with similar malignant potential like that of an intrauterine molar pregnancy. We report an uncommon case of EMG diagnosed by ultrasonography (USG) with a brief literature review. A 36-year-multipara presented at 8-weeks gestational age with severe abdominal pain and spotting. She underwent a spontaneous abortion 4 months back. Current transabdominal USG revealed a large right adnexal hydatidiform mole with moderate hemoperitoneum. Right ovary could not be discerned separately. Emergency laparotomy with hysterectomy and right adnexal clearance was done. Histopathology showed complete ectopic hydatidiform mole. USG remains the modality of choice for initial assessment of suspected GTD and it allows reliable evaluation of residual or recurrent disease. This report emphasizes the role of USG in the diagnosis of EMG and also, the importance of including EMG in the differential diagnosis of suspected ectopic pregnancy.

摘要

妊娠滋养细胞疾病(GTD)包括葡萄胎、侵袭性葡萄胎、上皮样滋养细胞肿瘤、胎盘部位滋养细胞肿瘤和绒癌。异位性葡萄胎妊娠(EMG)极为罕见,但恶性潜能与宫内葡萄胎妊娠相似。我们报告了一例经超声检查(USG)诊断的罕见病例,并进行了简要的文献复习。一名 36 岁多产妇在 8 周妊娠龄时出现严重腹痛和阴道出血。她在 4 个月前发生自然流产。目前的经腹 USG 显示右侧附件区有一个大的葡萄胎,伴中等量的腹腔积血。无法单独分辨右侧卵巢。行急诊剖腹手术,行子宫切除术和右侧附件切除术。组织病理学显示完全性异位葡萄胎。USG 仍然是疑似 GTD 初始评估的首选方法,它可以可靠地评估残留或复发性疾病。本报告强调了 USG 在诊断 EMG 中的作用,也强调了在疑似异位妊娠的鉴别诊断中包括 EMG 的重要性。

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本文引用的文献

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A Molar Pregnancy within the Fallopian Tube.输卵管内的葡萄胎妊娠。
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Eur J Obstet Gynecol Reprod Biol. 2007 Mar;131(1):85-88. doi: 10.1016/j.ejogrb.2006.03.004. Epub 2006 Apr 18.
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