Department of Dermatology, KK Women's & Children's Hospital, Singapore.
J Paediatr Child Health. 2024 Oct;60(10):538-543. doi: 10.1111/jpc.16634. Epub 2024 Aug 6.
Urticaria multiforme is an uncommon presentation of acute urticaria. It most commonly affects children and most often occurs secondary to an underlying viral infection. We performed a retrospective review of a cohort of Asian children with urticaria multiforme and reviewed the literature on the condition.
We retrospectively reviewed the clinical notes of children and adolescents less than 16 years of age, diagnosed with urticaria multiforme at our tertiary paediatric hospital between January 2017 and December 2022. Data collected and analysed included age, gender, initial diagnosis, antecedent symptoms, recent immunisations and medications, results of diagnostic tests, treatment and outcome.
A total of 20 children were identified, with median age of diagnosis of 1.9 years, with most patients (79%) 7 years of age or younger. Viral infections were the commonest triggers. The most common referring diagnoses were erythema multiforme and Stevens-Johnson syndrome. Common antecedent or concomitant symptoms were fever and upper respiratory symptoms. Blood investigations were generally unremarkable except for mildly increased white cell counts and other markers of infection. Outcomes were good in all patients, with resolution of symptoms within 6 weeks without sequelae.
Urticaria multiforme is an uncommon presentation of acute urticaria. Despite its striking appearance, it is generally a benign, self-limiting condition. Extensive investigations are usually not required and management is largely supportive.
多形性红斑是一种不常见的急性荨麻疹表现。它最常影响儿童，最常继发于潜在的病毒感染。我们对一组患有多形性红斑的亚洲儿童进行了回顾性研究，并回顾了关于该病的文献。
我们回顾性分析了 2017 年 1 月至 2022 年 12 月期间在我们的三级儿科医院诊断为多形性红斑的年龄在 16 岁以下的儿童和青少年的临床记录。收集和分析的数据包括年龄、性别、初始诊断、前驱症状、最近的免疫接种和药物治疗、诊断性检查结果、治疗和结果。
共确定了 20 例儿童，中位诊断年龄为 1.9 岁，大多数患者（79%）为 7 岁或以下。病毒感染是最常见的诱因。最常见的转诊诊断为多形性红斑和史蒂文斯-约翰逊综合征。常见的前驱或伴随症状是发热和上呼吸道症状。血液检查通常无明显异常，除了白细胞计数和其他感染标志物略有升高。所有患者的结局均良好，症状在 6 周内缓解，无后遗症。
多形性红斑是急性荨麻疹的一种不常见表现。尽管其表现明显，但通常是一种良性、自限性疾病。通常不需要进行广泛的检查，治疗主要是支持性的。
