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普氏黄酮菌血症伴弥漫性腹膜炎:一例报告及文献综述

Flavonifractor plautii Bacteremia With Generalized Peritonitis: A Case Report and Literature Review.

作者信息

Saito Shogo, Baba Shigeaki, Nikai Haruka, Fujisawa Ryosuke, Fujiwara Tohru

机构信息

Division of Central Clinical Laboratory, Iwate Medical University Hospital, Yahaba, JPN.

Department of Surgery, Iwate Medical University School of Medicine, Yahaba, JPN.

出版信息

Cureus. 2024 Jul 5;16(7):e63890. doi: 10.7759/cureus.63890. eCollection 2024 Jul.

Abstract

is an obligate anaerobic rod bacterium that is part of the human gut microbiota. We describe a case of bacteremia caused by in a mildly immunocompromised patient with acute generalized peritonitis. The patient is an 83-year-old male, with a history of stage III hepatocellular carcinoma 11 months prior, stage I gastric cancer, and cerebral infarction three months prior. He visited the emergency room of our hospital with a chief complaint of right-sided abdominal pain. A partial resection of the colon was performed due to stenosis of the transverse colon. Due to increasing abdominal pain, the patient underwent surgery for acute generalized peritonitis on the 11th postoperative day. was detected in blood cultures collected prior to surgery, and the patient was treated with piperacillin/tazobactam 2.25 g four times a day for 11 days. The patient resumed eating and was discharged with no recurrence. This species may also stain gram-negative, and caution should be exercised in reporting results due to the potential impact on initial antimicrobial therapy. Gram staining showed variation in the length of the bacterium, which is considered a characteristic of this species. Appropriate antimicrobial therapy for has yet to be established, and further accumulation of cases is needed to understand the resistance mechanism and confirm the effectiveness of different antimicrobials.

摘要

是一种专性厌氧杆菌,属于人体肠道微生物群的一部分。我们描述了一例由其引起的菌血症病例,该病例发生在一名患有急性弥漫性腹膜炎的轻度免疫功能低下患者身上。患者为一名83岁男性,11个月前有III期肝细胞癌病史,3个月前有I期胃癌和脑梗死病史。他因右侧腹痛为主诉就诊于我院急诊室。由于横结肠狭窄,行结肠部分切除术。术后第11天,因腹痛加重,患者接受了急性弥漫性腹膜炎手术。术前采集的血培养中检测到该菌,患者接受哌拉西林/他唑巴坦2.25 g每日4次治疗11天。患者恢复进食,出院后无复发。该菌种也可能革兰氏染色阴性,由于对初始抗菌治疗可能产生影响,在报告结果时应谨慎。革兰氏染色显示该菌长度存在差异,这被认为是该菌种的一个特征。针对该菌的适当抗菌治疗尚未确立,需要进一步积累病例以了解耐药机制并确认不同抗菌药物的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7e8/11298329/bf9753ecf5ff/cureus-0016-00000063890-i01.jpg

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