Katsuta Leona, Fujioka Tomoyuki, Kubota Kazunori, Mori Mio, Yamaga Emi, Yashima Yuka, Sato Arisa, Adachi Mio, Ishiba Toshiyuki, Oda Goshi, Nakagawa Tsuyoshi, Tateishi Ukihide
Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8510, Japan.
Department of Radiology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minamikoshigaya, Koshigaya, Saitama, 343 - 8555, Japan.
J Med Ultrason (2001). 2024 Oct;51(4):627-633. doi: 10.1007/s10396-024-01482-4. Epub 2024 Aug 6.
To compare different biopsy systems with different-sized needles by determining the weight of the tissue cores, which is one of the important factors for precise pathological diagnoses, and to provide a rationale for choosing the appropriate breast biopsy system with the appropriate needle for breast cancer biopsy.
Six different vacuum-assisted biopsy (VAB) systems and one core needle biopsy (CNB) system with different-sized needles in different modes were compared, representing 15 total combinations. Tissue cores were obtained from a chicken breast phantom, which is a common substitute for human breast tissue. Five cores were taken for each combination and weighed.
The CNB combination provided significantly lighter tissue cores compared with the VAB combinations with the same-size (14-G) needle (P < 0.01). The combinations using the thickest needle obtained the heaviest among all systems (P < 0.02). The untethered battery-free VAB system yielded the lightest specimen among the VAB systems with the same-sized (12-G) needle (P < 0.04). The percent coefficient of variation (%CV) of the core weights obtained using VAB without a basket was significantly smaller compared with the core weights obtained using VAB with a basket (P < 0.01).
VAB systems can yield larger tissue cores compared with CNB systems. The size of the tissue cores varies even with the same-sized needle among different VAB systems. When performing a breast tissue biopsy, it is important to consider not only CNB versus VAB but also what specific device to use with which needle size.
通过测定组织芯的重量来比较不同活检系统及不同尺寸的活检针，组织芯重量是精确病理诊断的重要因素之一，并为乳腺癌活检选择合适的乳腺活检系统及合适的活检针提供依据。
比较了六种不同的真空辅助活检（VAB）系统和一种不同模式下具有不同尺寸活检针的芯针活检（CNB）系统，共代表15种组合。组织芯取自鸡胸模型，这是一种常用的人体乳腺组织替代物。每种组合取五个组织芯并称重。
与使用相同尺寸（14G）活检针的VAB组合相比，CNB组合的组织芯明显更轻（P < 0.01）。在所有系统中，使用最粗活检针的组合获得的组织芯最重（P < 0.02）。在使用相同尺寸（12G）活检针的VAB系统中，无电池无线VAB系统获得的标本最轻（P < 0.04）。与使用带篮筐的VAB获得的组织芯重量相比，使用不带篮筐的VAB获得的组织芯重量的变异系数百分比（%CV）显著更小（P < 0.01）。
与CNB系统相比，VAB系统能获取更大的组织芯。即使在不同VAB系统中使用相同尺寸的活检针，组织芯的大小也会有所不同。在进行乳腺组织活检时，不仅要考虑CNB与VAB的区别，还要考虑具体使用哪种设备及何种尺寸的活检针。
