Department of Joint Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Orthop Surg. 2024 Nov;16(11):2708-2713. doi: 10.1111/os.14183. Epub 2024 Aug 6.
Posterior condylar offset (PCO) and anterior condylar offset (ACO) exert an influence on the sagittal alignment in total knee arthroplasty (TKA). However, there is no common consensus that the variation range of posterior condylar offset (PCO) is associated with patient-reported outcome measures (PROMs) and the optimum variation range of PCO. This study aims to investigate the correlation between PCO and the PROMs of primary TKA for osteoarthritis (OA) and find out the optimal variation range of the PCO.
In this study, we performed a radiographic analysis of 106 patients (112 knees) with primary TKA. Patients were divided into two cohorts (A and B) according to the Western Ontario and McMaster Universities Osteoarthritis index (WOMAC). Correlations between the sagittal parameter and WOMAC were investigated using univariate and multivariate analysis. The receiver operating characteristic (ROC) curve was used to establish the cut-off value for the optimal variation range. We then further investigated how different variation range affects the WOMAC subscale score and forgotten-joint-score-12 (FJS-12).
Univariate analysis revealed a correlation between the variation range of PCO (p < 0.01), ACO (p < 0.01) and PROMs. Multivariate analysis showed that only PCO was associated with PROMs. In the ROC graph, the cut-off value of the variation range of PCO is 2.85 mm (AUC = 0.66, Youden index = 0.26). The WOMAC functional ability score of the group outside the PCO variation range of 2.85 mm significantly increased compared to the group within the range.
In this study, PCO variation was significantly associated with clinical outcomes in TKA and the optimal PCO variation range was within 2.85 mm. Maintaining the PCO variation within 2.85 mm could enhance functional recovery and patient satisfaction.
髁后间距(PCO)和髁前间距(ACO)对全膝关节置换术(TKA)中的矢状面对线有影响。然而,目前还没有普遍共识认为髁后间距(PCO)的变化范围与患者报告的结局测量(PROMs)和 PCO 的最佳变化范围有关。本研究旨在探讨原发性 TKA 治疗骨关节炎(OA)的 PCO 与 PROMs 的相关性,并找出 PCO 的最佳变化范围。
本研究对 106 例(112 膝)接受原发性 TKA 的患者进行了影像学分析。根据安大略西部和麦克马斯特大学骨关节炎指数(WOMAC),患者被分为两组(A 组和 B 组)。使用单变量和多变量分析研究矢状参数与 WOMAC 之间的相关性。使用受试者工作特征(ROC)曲线确定最佳变化范围的截断值。然后,我们进一步研究了不同变化范围如何影响 WOMAC 亚量表评分和遗忘关节评分-12(FJS-12)。
单变量分析显示 PCO 变化范围(p < 0.01)、ACO 变化范围(p < 0.01)与 PROMs 之间存在相关性。多变量分析显示只有 PCO 与 PROMs 相关。在 ROC 图中,PCO 变化范围的截断值为 2.85mm(AUC=0.66,Youden 指数=0.26)。PCO 变化范围在 2.85mm 之外的组的 WOMAC 功能能力评分明显高于在范围之内的组。
在本研究中,PCO 变化与 TKA 的临床结果显著相关,最佳 PCO 变化范围在 2.85mm 以内。保持 PCO 变化在 2.85mm 以内可以增强功能恢复和患者满意度。