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家门口的敌人:肉毒中毒。

The enemy at the gate: Botulism.

作者信息

Taşkın Ömer, Akpınar Ayça Açıkalın

机构信息

Emergency Service, Yüreğir State Hospital, Adana, Türkiye.

Department of Emergency Medicine, Çukurova University, Adana, Türkiye.

出版信息

Turk J Emerg Med. 2024 Jul 1;24(3):127-132. doi: 10.4103/tjem.tjem_80_24. eCollection 2024 Jul-Sep.

DOI:10.4103/tjem.tjem_80_24
PMID:39108685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11299839/
Abstract

Botulism, caused by , continues to pose a significant threat to public health. This review explores the historical context and contemporary relevance of botulism, emphasizing its potential lethality and evolving medical applications. In recent years, the use of botulinum toxin in medical procedures, particularly in cosmetic and therapeutic applications, has increased the risk of iatrogenic botulism. The rise in iatrogenic cases underscores the importance of vigilance among health-care providers, especially those in emergency departments, where prompt diagnosis and intervention are critical. This review underscores the necessity for health-care professionals to consider botulism in the differential diagnosis of patients presenting with relevant symptoms, given the potential severity of the condition.

摘要

由[未提及具体病因]引起的肉毒中毒仍然对公众健康构成重大威胁。本综述探讨了肉毒中毒的历史背景和当代相关性,强调了其潜在的致命性以及不断发展的医学应用。近年来,肉毒杆菌毒素在医疗程序中的使用,特别是在美容和治疗应用中,增加了医源性肉毒中毒的风险。医源性病例的增加凸显了医疗保健提供者保持警惕的重要性,尤其是急诊科的医护人员,在那里及时诊断和干预至关重要。鉴于病情的潜在严重性,本综述强调医疗保健专业人员在对出现相关症状的患者进行鉴别诊断时必须考虑肉毒中毒。

相似文献

1
The enemy at the gate: Botulism.家门口的敌人:肉毒中毒。
Turk J Emerg Med. 2024 Jul 1;24(3):127-132. doi: 10.4103/tjem.tjem_80_24. eCollection 2024 Jul-Sep.
2
Iatrogenic botulism cases after gastric and axillary application of botulinum toxin and review of literature.胃和腋窝应用肉毒毒素后医源性肉毒中毒病例及文献复习。
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Delayed Antitoxin Treatment of Two Adult Patients with Botulism after Cosmetic Injection of Botulinum Type A Toxin.两例成人A型肉毒毒素美容注射后肉毒中毒的抗毒素延迟治疗
J Emerg Med. 2016 Dec;51(6):677-679. doi: 10.1016/j.jemermed.2016.07.097. Epub 2016 Sep 28.
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Infant Botulism.婴儿肉毒中毒
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From Beauty to Botulism: A Case Report Highlighting the Rare Risk of Botox Administration.从美容到肉毒中毒:一例报告凸显肉毒杆菌毒素注射的罕见风险
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[Botulism: prevention, clinical diagnostics, therapy and possible threat].[肉毒中毒:预防、临床诊断、治疗及潜在威胁]
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本文引用的文献

1
Iatrogenic botulism.医源性肉毒中毒。
Tidsskr Nor Laegeforen. 2024 Feb 12;144(2). doi: 10.4045/tidsskr.23.0625. Print 2024 Feb 13.
2
Outbreaks of iatrogenic botulism in Europe: Combating off-label medical use of Botulinum Neurotoxin (BoNT) in bariatric procedures.欧洲医源性肉毒中毒疫情:应对肉毒杆菌神经毒素(BoNT)在减肥手术中的非标签医疗用途。
New Microbes New Infect. 2023 May 22;53:101152. doi: 10.1016/j.nmni.2023.101152. eCollection 2023 Jun.
3
Epidemiological Analysis of Foodborne Botulism Outbreaks - China, 2004-2020.2004 - 2020年中国食源性肉毒中毒暴发的流行病学分析
China CDC Wkly. 2022 Sep 2;4(35):788-792. doi: 10.46234/ccdcw2022.114.
4
Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.2021 年肉毒中毒诊断和治疗临床指南。
MMWR Recomm Rep. 2021 May 7;70(2):1-30. doi: 10.15585/mmwr.rr7002a1.
5
Engineering Botulinum Neurotoxins for Enhanced Therapeutic Applications and Vaccine Development.工程肉毒神经毒素用于增强治疗应用和疫苗开发。
Toxins (Basel). 2020 Dec 22;13(1):1. doi: 10.3390/toxins13010001.
6
Adult Intestinal Botulism: A Rare Presentation in an Immunocompromised Patient With Short Bowel Syndrome.成人肠道肉毒中毒:短肠综合征免疫功能低下患者的罕见表现。
Mayo Clin Proc Innov Qual Outcomes. 2018 Aug 3;2(3):291-296. doi: 10.1016/j.mayocpiqo.2018.06.005. eCollection 2018 Sep.
7
Clinical Characteristics and Ancillary Test Results Among Patients With Botulism-United States, 2002-2015.2002-2015 年美国肉毒梭菌中毒患者的临床特征和辅助检查结果。
Clin Infect Dis. 2017 Dec 27;66(suppl_1):S4-S10. doi: 10.1093/cid/cix935.
8
Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923-2016.抗毒素治疗在治疗食源性肉毒中毒患者中的疗效:1923-2016 年病例的系统评价和荟萃分析。
Clin Infect Dis. 2017 Dec 27;66(suppl_1):S43-S56. doi: 10.1093/cid/cix815.
9
Clinical Criteria to Trigger Suspicion for Botulism: An Evidence-Based Tool to Facilitate Timely Recognition of Suspected Cases During Sporadic Events and Outbreaks.临床触发肉毒中毒怀疑的标准:一种有助于在散发事件和暴发期间及时识别疑似病例的基于证据的工具。
Clin Infect Dis. 2017 Dec 27;66(suppl_1):S38-S42. doi: 10.1093/cid/cix814.
10
Botulism During Pregnancy and the Postpartum Period: A Systematic Review.妊娠期和产后期的肉毒中毒:系统评价。
Clin Infect Dis. 2017 Dec 27;66(suppl_1):S30-S37. doi: 10.1093/cid/cix813.