Grund Caroline, Kerner Dorothea, Driulini Deborah, Schneider Günther
Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum des Saarlandes, Kirrbergerstraße 100, 66421, Homburg/Saar, Deutschland.
Radiologie (Heidelb). 2024 Sep;64(9):728-738. doi: 10.1007/s00117-024-01348-3. Epub 2024 Aug 7.
Malignant soft tissue tumors, in particular, require a multimodal treatment concept involving interdisciplinary cooperation between radiologists, pathologists, surgeons and oncologists at special tumor centers. The foundations of the treatment decision are the imaging diagnostics and the diagnosis confirmation based on tissue samples. The (local) extent and growth behavior of a tumor are among the most important findings of imaging as they have a direct influence on the surgical procedure. The most important diagnostic procedure here is magnetic resonance imaging (MRI). The T1-weighted and fat-suppressed sequences after i.v. contrast administration are used to visualize the extent of the tumor. In synopsis with diffusion-weighted and T2-weighted sequences, a differentiation between vital tumor tissue and tumor necrosis is additionally possible. This also enables targeted sampling from vital tumor parts so that the patient can be assigned to the appropriate treatment concept as quickly as possible.
特别是恶性软组织肿瘤，需要一种多模式治疗理念，这涉及到特殊肿瘤中心的放射科医生、病理科医生、外科医生和肿瘤内科医生之间的跨学科合作。治疗决策的基础是影像诊断以及基于组织样本的诊断确认。肿瘤的（局部）范围和生长行为是影像学最重要的发现之一，因为它们直接影响手术操作。这里最重要的诊断程序是磁共振成像（MRI）。静脉注射造影剂后的T1加权和脂肪抑制序列用于显示肿瘤范围。结合扩散加权序列和T2加权序列，还可以区分存活的肿瘤组织和肿瘤坏死。这也使得能够从存活的肿瘤部位进行靶向取样，从而使患者能够尽快被分配到合适的治疗方案中。
