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一项关于药师临床活动及其对多发性骨髓瘤患者护理影响的范围综述。

A scoping review of pharmacists' clinical activities and impact on the care of patients with multiple myeloma.

机构信息

Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580 - Conj. das Químicas, Bloco 13, Cidade Universitária Butantã, São Paulo, SP, Brazil.

Department of Pharmacy, Federal University of Paraná, Curitiba, Brazil.

出版信息

Int J Clin Pharm. 2024 Dec;46(6):1281-1293. doi: 10.1007/s11096-024-01787-x. Epub 2024 Aug 7.

Abstract

BACKGROUND

Treating multiple myeloma is complex, and providing supportive care through an interdisciplinary approach is essential.

AIM

To report and synthesize pharmacists' clinical activities and impact on the care of patients with multiple myeloma.

METHOD

This was a scoping review that followed the PRISMA-ScR reporting recommendations. A search was conducted in PubMed, Embase, Web of Science, Scopus, and LILACS from the inception of the database until January 10th, 2024. Papers that reported pharmacists' clinical activities in the care of patients with multiple myeloma were included. Descriptive Elements of Pharmacist Intervention Characterization Tool (DEPICT) version 2 was used to characterize the pharmacists' clinical activities. The results are presented as a narrative and tabular synthesis.

RESULTS

A total of 2885 records were identified, 10 of which met the inclusion criteria. Pharmacists' clinical activities related to 'direct patient care' (n = 8) and 'medication counseling, education, and training' (n = 7) were the most cited. Most were provided for patients (n = 8), by one-on-one contact (n = 9), and through face-to-face communication method (n = 8), with patient counseling being the main action taken by pharmacists (n = 7). Materials that supported pharmacists' actions were cited in five studies. Integrating pharmacists into interdisciplinary teams led to improved process, clinical, humanistic, and economic outcomes.

CONCLUSION

This scoping review emphasizes pharmacists' clinical activities in improving the care of patients with multiple myeloma. There is a need to develop studies with patient-reported outcomes and comprehensive reporting of pharmacists' clinical activities to ensure reproducibility and effective implementation in clinical practice.

摘要

背景

多发性骨髓瘤的治疗较为复杂,通过跨学科方法提供支持性护理至关重要。

目的

报告并综合药师在多发性骨髓瘤患者护理中的临床活动及其对患者护理的影响。

方法

这是一项范围性综述,遵循 PRISMA-ScR 报告建议。从数据库创建开始,在 PubMed、Embase、Web of Science、Scopus 和 LILACS 中进行了检索,检索截止日期为 2024 年 1 月 10 日。纳入报告药师在多发性骨髓瘤患者护理中临床活动的论文。使用药师干预特征描述工具(DEPICT)版本 2 描述药师的临床活动特征。结果以叙述和表格形式呈现。

结果

共确定了 2885 条记录,其中有 10 篇符合纳入标准。药师与“直接患者护理”(n=8)和“药物咨询、教育和培训”(n=7)相关的临床活动被引用最多。大多数是为患者提供的(n=8),通过一对一的接触(n=9),并通过面对面的沟通方式(n=8)进行,药师的主要行动是对患者进行咨询(n=7)。有 5 项研究引用了支持药师行动的材料。将药师纳入多学科团队可改善流程、临床、人文和经济结果。

结论

本范围性综述强调了药师在改善多发性骨髓瘤患者护理方面的临床活动。需要开展以患者报告结局为重点并全面报告药师临床活动的研究,以确保在临床实践中的可重复性和有效实施。

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