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Nortriptyline and fluphenazine in the symptomatic treatment of diabetic neuropathy. A double-blind cross-over study.

作者信息

Gomez-Perez Francisco J, Rull Juan A, Dies Haroldo, Rodriguez-Rivera Guillermo J, Gonzalez-Barranco Jorge, Lozano-Castañeda Oscar

机构信息

Departamento de Diabetes y Metabolismo de Lipidos, Instituto National de la Nutricion 'Salvador Zubiran,' Vasco de Quiroga 15, Delegation Tlalpan, Mexico City, D.F. 14000 Mexico.

出版信息

Pain. 1985 Dec;23(4):395-400. doi: 10.1016/0304-3959(85)90010-7.

DOI:10.1016/0304-3959(85)90010-7
PMID:3911140
Abstract

A controlled clinical trial on the efficacy of a nortriptyline-fluphenazine combination was carried out in patients with painful diabetic polyneuropathy. A visual analog scale was used to evaluate the relief of pain or paresthesia. Significant relief of both pain and paresthesia was obtained with this combination. The differences were statistically significant. Side effects were frequent but not usually severe enough to lead to cessation of these medications.

摘要

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