Fournier J P, Marty P, Bernard E, Leloire P, Dellamonica P, Le Fichoux Y
Pathol Biol (Paris). 1985 Jun;33(5 Pt 2):611-3.
Two patients with hydatid cysts of the spine were given albendazole. One patient had previously been treated by surgery followed by flubendazole. Albendazole was well tolerated in both cases. Follow-up evaluations included clinical, roentgenological, serological and, in one case, histological investigations. Albendazole sulfoxide levels were assayed in plasma samples from one patient and in non-diseased bone in the other. The treatment seems to have been effective in both patients, suggesting that albendazole may be of value in hydatid disease of the bone. Confirmatory evidence from a larger series is needed.
两名患有脊柱包虫囊肿的患者接受了阿苯达唑治疗。一名患者此前曾接受手术治疗,随后服用氟苯达唑。两名患者对阿苯达唑的耐受性均良好。随访评估包括临床、放射学、血清学检查,其中一例还进行了组织学检查。对一名患者的血浆样本和另一名患者的正常骨骼进行了阿苯达唑亚砜水平检测。治疗似乎对两名患者均有效,这表明阿苯达唑在骨包虫病中可能具有一定价值。需要更多病例的证实性证据。