Department of Orthopaedics, China-Japan Friendship Hospital, Beijing, China.
J Coll Physicians Surg Pak. 2024 Aug;34(8):981-984. doi: 10.29271/jcpsp.2024.08.981.
To investigate the frequency of deep vein thrombosis (DVT) in patients aged over 80 years on admission after intertrochanteric femur fracture and to explore the risk factors of DVT.
Descriptive study. Place and Duration of the Study: Department of Orthopaedics, China-Japan Friendship Hospital, Beijing, China, from 1st January 2019 to 31st December 2022.
A group of patients aged over 80 years with intertrochanteric fracture were included according to the presence or absence of DVT confirmed by ultrasonography on admission. The patients were divided into the non-DVT and DVT groups. Clinical data were retrospectively compared between the two groups and analysed by multivariate logistic regression to screen risk factors of DVT.
A total of 130 patients meeting the inclusion criteria were enrolled, and 37 of them had DVT on admission, with a prevalence of 28.5%, including 25 (67.6%) distal peripheral DVT, 11 (29.7%) proximal central DVT, and 1 (2.7%) mixed DVT. The American Society of Anaesthesiologists (ASA) classification, Charlson comorbidity index, the serum levels of D-dimer, fibrinogen degradation products, albumin, potassium, inorganic phosphorus, and calcium showed significant differences between the two groups (p <0.1). Multivariate analysis identified increased D-dimer (>6.005 mg/L), decreased albumin (<36.45 g/L), and reduced potassium (<3.650 mmol/L) as independent factors for DVT in aged intertrochanteric fracture patients (AIFPs).
A high incidence of DVT was revealed in AIFPs, and elevated D-dimer levels, reduced albumin levels, and reduced potassium concentrations were shown to be correlated to DVT.
Intertrochanteric fracture, Deep vein thrombosis, Aged patients, Risk factor, Multivariate logistic regression.
调查 80 岁以上股骨转子间骨折患者入院时深静脉血栓形成（DVT）的发生率，并探讨 DVT 的危险因素。
描述性研究。地点和研究时间：中国北京中日友好医院骨科，2019 年 1 月 1 日至 2022 年 12 月 31 日。
根据入院时超声检查是否确诊 DVT，纳入符合条件的 80 岁以上股骨转子间骨折患者。将患者分为非 DVT 组和 DVT 组。回顾性比较两组患者的临床资料，并采用多因素 logistic 回归分析筛选 DVT 的危险因素。
共纳入符合条件的 130 例患者，其中 37 例患者入院时发生 DVT，患病率为 28.5%，包括 25 例（67.6%）远端外周 DVT、11 例（29.7%）近端中央 DVT 和 1 例（2.7%）混合 DVT。两组患者的美国麻醉医师协会（ASA）分级、Charlson 合并症指数、血清 D-二聚体、纤维蛋白原降解产物、白蛋白、钾、无机磷和钙水平差异均有统计学意义（p<0.1）。多因素分析发现，D-二聚体升高（>6.005mg/L）、白蛋白降低（<36.45g/L）和钾降低（<3.650mmol/L）是老年股骨转子间骨折患者 DVT 的独立危险因素。
老年股骨转子间骨折患者 DVT 发生率较高，D-二聚体水平升高、白蛋白水平降低和钾浓度降低与 DVT 相关。
股骨转子间骨折；深静脉血栓形成；老年患者；危险因素；多因素 logistic 回归。
