Gong Rui, Jin Xi-Min, Xu Lian-You, Zhang Zhi-Meng, Yuan Dao-Tong, Xie Wen-Peng, Zhang Yong-Kui
First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Department of Orthopedic Surgery, Afliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Front Med (Lausanne). 2025 Jan 17;11:1503719. doi: 10.3389/fmed.2024.1503719. eCollection 2024.
Intertrochanteric fractures are one of the most common types of hip fractures, with delayed surgical treatment beyond 48 h associated with increased postoperative complications and mortality, especially in older adults. This study aimed to develop a predictive model for delayed preoperative waiting times in intertrochanteric fracture cases, based on previous research, to offer a valuable reference for clinical decision-making.
A retrospective analysis was conducted on 1,116 patients with intertrochanteric fractures admitted to the Affiliated Hospital of Shandong University of Traditional Chinese Medicine for internal fixation surgery from January 2017 to January 2024. Patient demographic data and clinical examination results were collected. A logistic regression model was used to construct a predictive model, which was then visualized through a nomogram. The model's performance was subsequently validated.
The predictive model developed from 728 patients in the training cohort, identified key predictors, including age, sex, lower extremity deep vein thrombosis, injury location, and biochemical markers. The model demonstrated strong discriminative ability, with an area under the receiver operating characteristic curve of 0.749 (95% confidence interval: 0.621-0.801) for the training set, and 0.745 in the validation set. Calibration curves indicated that the predicted risk of surgical delay closely aligned with observed outcomes. Furthermore, decision curve analysis verified the model's clinical utility, demonstrating its effectiveness in guiding treatment decisions.
The nomogram model developed in this study provides a reliable tool for predicting delayed surgical intervention in patients with intertrochanteric femur fractures. It offers clinicians a valuable reference to anticipate delays in surgical treatment and aids in the formulation of more timely and appropriate treatment strategies, potentially improving patient outcomes.
转子间骨折是最常见的髋部骨折类型之一,手术治疗延迟超过48小时会增加术后并发症和死亡率,尤其是在老年人中。本研究旨在基于先前的研究,开发一种预测转子间骨折病例术前等待时间延迟的模型,为临床决策提供有价值的参考。
对2017年1月至2024年1月在山东中医药大学附属医院接受内固定手术的1116例转子间骨折患者进行回顾性分析。收集患者的人口统计学数据和临床检查结果。使用逻辑回归模型构建预测模型,然后通过列线图进行可视化。随后对模型的性能进行验证。
从训练队列中的728例患者开发的预测模型确定了关键预测因素,包括年龄、性别、下肢深静脉血栓形成、损伤部位和生化标志物。该模型具有很强的判别能力,训练集的受试者操作特征曲线下面积为0.749(95%置信区间:0.621-0.801),验证集为0.745。校准曲线表明,手术延迟的预测风险与观察结果密切相关。此外,决策曲线分析验证了该模型的临床实用性,证明了其在指导治疗决策方面的有效性。
本研究开发的列线图模型为预测股骨转子间骨折患者手术干预延迟提供了可靠工具。它为临床医生提供了一个有价值的参考,以预测手术治疗的延迟,并有助于制定更及时和适当的治疗策略,可能改善患者的预后。