内分泌腺及靶器官癌症：遗传学考量
Cancer of endocrine glands and target organs: genetic considerations.
作者信息
Garnica A D, Frias J L
出版信息
Ann Clin Lab Sci. 1979 Nov-Dec;9(6):445-54.
PMID:391136
Abstract
The pathogenesis of cancer in general is influenced by many factors, genetic and environmental. Epidemiological studies demonstrate familial aggregation of cancer in a significant proportion of cases. Many of these familial cancer syndromes contain endocrine hormone-related components. The etiology of endocrine-related cancers is complex, as is that of other cancers. Tumors of endocrine glands and target organs are subject to the same influences as other cancers; an additional variable is that of hormone-responsiveness.
摘要
一般来说，癌症的发病机制受多种因素影响，包括遗传因素和环境因素。流行病学研究表明，相当一部分癌症病例存在家族聚集性。许多这些家族性癌症综合征都包含与内分泌激素相关的成分。与内分泌相关的癌症病因复杂，其他癌症的病因也是如此。内分泌腺和靶器官的肿瘤与其他癌症受到相同的影响；另一个变量是激素反应性。
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