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Clinical spectrum of disease and outcomes in children with Omicron SARS-COV-2 infection in Cape Town, South Africa.南非开普敦感染奥密克戎新冠病毒的儿童的疾病临床谱及转归
IJTLD Open. 2024 Jan 1;1(1):27-33. doi: 10.5588/ijtldopen.23.0053. eCollection 2024 Jan.
2
Clinical Presentation and Outcome of Acute Respiratory Illnesses in South African Children During the COVID-19 Pandemic.南非儿童在 COVID-19 大流行期间急性呼吸道疾病的临床特征和转归。
Pediatr Infect Dis J. 2023 Aug 1;42(8):672-678. doi: 10.1097/INF.0000000000003951. Epub 2023 Jul 13.
3
Pediatric coronavirus disease 2019 in Africa.非洲的儿童 2019 冠状病毒病。
Curr Opin Pediatr. 2023 Apr 1;35(2):176-183. doi: 10.1097/MOP.0000000000001230. Epub 2023 Feb 20.
4
The intersecting pandemics of tuberculosis and COVID-19: population-level and patient-level impact, clinical presentation, and corrective interventions.结核病和 COVID-19 大流行的交织:人群层面和患者层面的影响、临床表现和纠正干预措施。
Lancet Respir Med. 2022 Jun;10(6):603-622. doi: 10.1016/S2213-2600(22)00092-3. Epub 2022 Mar 23.
5
Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries.撒哈拉以南非洲 6 国儿童和青少年 COVID-19 住院患者临床结局评估。
JAMA Pediatr. 2022 Mar 1;176(3):e216436. doi: 10.1001/jamapediatrics.2021.6436. Epub 2022 Mar 7.
6
Global, regional, and national causes of under-5 mortality in 2000-19: an updated systematic analysis with implications for the Sustainable Development Goals.2000-19 年全球、区域和国家 5 岁以下儿童死亡原因:一项更新的系统分析及其对可持续发展目标的影响。
Lancet Child Adolesc Health. 2022 Feb;6(2):106-115. doi: 10.1016/S2352-4642(21)00311-4. Epub 2021 Nov 17.
7
Clinical characteristics, treatment and outcomes of paediatric COVID-19: a systematic review and meta-analysis.儿童 COVID-19 的临床特征、治疗和结局:系统评价和荟萃分析。
Arch Dis Child. 2021 Apr 21;106(5):440-448. doi: 10.1136/archdischild-2020-321385.
8
Tuberculosis and COVID-19 interaction: A review of biological, clinical and public health effects.结核病与 COVID-19 的相互作用:生物学、临床和公共卫生影响的综述。
Pulmonology. 2021 Mar-Apr;27(2):151-165. doi: 10.1016/j.pulmoe.2020.12.012. Epub 2021 Jan 22.
9
The differential impact of pediatric COVID-19 between high-income countries and low- and middle-income countries: A systematic review of fatality and ICU admission in children worldwide.高收入国家与中低收入国家儿童 COVID-19 之间的差异影响:全球儿童病死率和 ICU 入院率的系统评价。
PLoS One. 2021 Jan 29;16(1):e0246326. doi: 10.1371/journal.pone.0246326. eCollection 2021.
10
Systematic review of reviews of symptoms and signs of COVID-19 in children and adolescents.儿童和青少年 COVID-19 症状和体征的系统评价综述。
Arch Dis Child. 2021 Jul 19;106(8):802-807. doi: 10.1136/archdischild-2020-320972.

儿童新冠病毒病:南非一家地区医院的临床表现及住院病程

COVID-19 in children: Clinical presentation and hospital course at a district hospital in South Africa.

作者信息

Nieuwoudt Mareli, O'Connell Natasha L, van der Zalm Marieke M, Redfern Andrew W, Rabie Helena

机构信息

Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Department of Paediatrics and Child Health, Khayelitsha Hospital, Cape Town, South Africa.

出版信息

S Afr J Infect Dis. 2024 Jul 8;39(1):580. doi: 10.4102/sajid.v39i1.580. eCollection 2024.

DOI:10.4102/sajid.v39i1.580
PMID:39114259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11304354/
Abstract

UNLABELLED

Limited data exist on South African children hospitalised with COVID-19 in district hospitals. We describe the presentation and outcomes of children admitted to a level 1 and 2 hospital and compare this with children admitted to a level 2 and 3 hospital.

CONTRIBUTION

This study highlights that young age is an important risk factor for hospitalisation with severe COVID-19. Infants with HIV exposure and prematurity are disproportionately represented among admissions. Furthermore, we notice a high number of children with current or new tuberculosis confirming the interplay between viral infections and childhood tuberculosis.

摘要

未标注

关于在地区医院因新冠肺炎住院的南非儿童的数据有限。我们描述了入住一级和二级医院的儿童的临床表现和治疗结果,并将其与入住二级和三级医院的儿童进行比较。

贡献

本研究强调,年龄小是因严重新冠肺炎住院的一个重要风险因素。暴露于艾滋病毒的婴儿和早产儿在入院患者中所占比例过高。此外,我们注意到有大量患有现患或新发结核病的儿童,这证实了病毒感染与儿童结核病之间的相互作用。