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骨填充网袋技术与角椎体成形术治疗老年骨质疏松性胸腰椎压缩骨折的疗效

Effectiveness of bone-filled mesh bag technology and angle vertebroplasty in the treatment of osteoporotic thoracic vertebral compression fractures in the elderly.

作者信息

Tang Chenping, Liu Feiwen

机构信息

Xindu District People's Hospital of Chengdu Chengdu 610500, Sichuan, China.

出版信息

Am J Transl Res. 2024 Jul 15;16(7):3289-3297. doi: 10.62347/GHNQ5649. eCollection 2024.

DOI:10.62347/GHNQ5649
PMID:39114704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11301485/
Abstract

OBJECTIVE

To evaluate the effectiveness, pain level, and lung function in elderly patients with osteoporotic thoracic vertebral compression fractures using bone filling mesh bag technology compared to curved vertebroplasty.

METHODS

This retrospective analysis reviewed 72 elderly patients with osteoporotic thoracic vertebral compression fractures treated at Xindu District People's Hospital of Chengdu between February 2021 and January 2022. The patients were separated into two groups according to surgery approach: an observation group using bone filling mesh bag technology and a control group using curved vertebroplasty. The overall response rate, pain degree, pulmonary function, life quality grades, surgical indicators, and bone cement leakage rates of the two groups were evaluated.

RESULTS

The variation in overall response rate (P=0.420), pain degree (P=0.270), pulmonary function (peak expiratory flow: P=0.660, forced expiratory volume in the first second: P=0.775, forced vital capacity: 0.062), and life quality grades (physical health: P=0.949, social function: P=0.935, physiological function: P=0.970, vitality: P=0.778) between the observation group and the control group after treatment was not statistically meaningful. The Cobb angle (P<0.001) and vertebral height (P<0.001) of patients in the observation group were significantly higher than those in the control group after therapy. The leakage rates of bone cement (intervertebral disc leakage, paravertebral vein leakage, paravertebral soft tissue leakage) of patients in the observation group were notably lower than those in the control group after therapy (P=0.029).

CONCLUSION

Bone filling mesh bag technology offers significant improvements in Cobb angle and vertebral height for treating elderly patients with osteoporotic thoracic vertebral compression fractures, and reduced the leakage rate of bone cement. This technique achieves comparable therapeutic outcomes to curved vertebroplasty.

摘要

目的

比较骨填充网袋技术与经皮椎体后凸成形术治疗老年骨质疏松性胸腰椎压缩骨折的有效性、疼痛程度及肺功能。

方法

回顾性分析2021年2月至2022年1月在成都市新都区人民医院接受治疗的72例老年骨质疏松性胸腰椎压缩骨折患者。根据手术方式将患者分为两组:观察组采用骨填充网袋技术,对照组采用经皮椎体后凸成形术。评估两组的总有效率、疼痛程度、肺功能、生活质量分级、手术指标及骨水泥渗漏率。

结果

治疗后观察组与对照组的总有效率(P = 0.420)、疼痛程度(P = 0.270)、肺功能(呼气峰值流速:P = 0.660,第1秒用力呼气量:P = 0.775,用力肺活量:P = 0.062)及生活质量分级(生理健康:P = 0.949,社会功能:P = 0.935,生理功能:P = 0.970,活力:P = 第1秒用力呼气量:P = 0.775,用力肺活量:P = 0.062)差异无统计学意义。治疗后观察组患者的Cobb角(P < 0.001)和椎体高度(P < 0.001)显著高于对照组。治疗后观察组患者的骨水泥渗漏率(椎间盘渗漏、椎旁静脉渗漏、椎旁软组织渗漏)明显低于对照组(P = 0.029)。

结论

骨填充网袋技术在治疗老年骨质疏松性胸腰椎压缩骨折方面,在Cobb角和椎体高度方面有显著改善,并降低了骨水泥渗漏率。该技术与经皮椎体后凸成形术的治疗效果相当。

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