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一名年轻女性多发性骨髓瘤表现为侵袭性颅底肿瘤。

Multiple myeloma in a young female presenting as an aggressive skull-base tumour.

作者信息

Lesar Ursula, Janse van Rensburg Leon, Oelofsen Siobhan, McCree Kevin, Ackerman Christelle, Davis Razaan

机构信息

Department of Medical Imaging and Clinical Oncology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Academic Hospital, Cape Town, South Africa.

Department of Radiology and Diagnostics, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa.

出版信息

SA J Radiol. 2024 Jul 31;28(1):2883. doi: 10.4102/sajr.v28i1.2883. eCollection 2024.

DOI:10.4102/sajr.v28i1.2883
PMID:39114744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11304403/
Abstract

UNLABELLED

Plasma cell neoplasia has a wide presentation of disease (localised or systemic) according to the International Myeloma Working Group. Radiological imaging identifies plasmacytomas as solitary lesions or part of multiple myeloma. We present a rare case of a 21-year-old female who presented with a skull-base tumour.

CONTRIBUTION

A head and neck plasmacytoma with further lytic bone lesions was confirmed on imaging. This article presents and discusses the clinical, CT, MRI, positron emission tomography (PET)-CT, histology and laboratory findings.

摘要

未标注

根据国际骨髓瘤工作组的定义,浆细胞肿瘤有广泛的疾病表现(局限性或全身性)。放射影像学将浆细胞瘤识别为孤立性病变或多发性骨髓瘤的一部分。我们报告一例罕见的21岁女性,她患有颅底肿瘤。

贡献

影像学检查确诊为头颈部浆细胞瘤并伴有进一步的溶骨性骨病变。本文介绍并讨论了临床、CT、MRI、正电子发射断层扫描(PET)-CT、组织学和实验室检查结果。

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本文引用的文献

1
Rib Plasmacytoma With Unusual Sunburst Periosteal Reaction.肋骨浆细胞瘤伴不典型日光放射状骨膜反应。
Clin Nucl Med. 2020 Jun;45(6):461-462. doi: 10.1097/RLU.0000000000003030.
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Assessment of Nasopharyngeal Cancer in Young Patients Aged ≤ 30 Years.30岁及以下年轻患者的鼻咽癌评估
Front Oncol. 2019 Nov 6;9:1179. doi: 10.3389/fonc.2019.01179. eCollection 2019.
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Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria.全身多发性骨髓瘤成像:诊断标准。
Radiographics. 2019 Jul-Aug;39(4):1077-1097. doi: 10.1148/rg.2019180096.
4
Descriptive epidemiology and outcomes of bone sarcomas in adolescent and young adult patients in Japan.日本青少年和青年成人骨肉瘤患者的描述性流行病学及预后情况
BMC Musculoskelet Disord. 2018 Aug 18;19(1):297. doi: 10.1186/s12891-018-2217-1.
5
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel.孤立性浆细胞瘤的诊断、治疗和反应评估:欧洲专家小组的最新建议。
J Hematol Oncol. 2018 Jan 16;11(1):10. doi: 10.1186/s13045-017-0549-1.
6
Solitary Plasmacytoma.孤立性浆细胞瘤
Mediterr J Hematol Infect Dis. 2017 Aug 23;9(1):e2017052. doi: 10.4084/MJHID.2017.052. eCollection 2017.
7
Incidence, characteristics, and outcome of solitary plasmacytoma and plasma cell leukemia. Population-based data from the Swedish Myeloma Register.孤立性浆细胞瘤和浆细胞白血病的发病情况、特征和结局。来自瑞典骨髓瘤登记处的基于人群的数据。
Eur J Haematol. 2017 Sep;99(3):216-222. doi: 10.1111/ejh.12907. Epub 2017 Jun 28.
8
Plasmacytoma of the Skull Base: A Meta-Analysis.颅底浆细胞瘤:一项荟萃分析
J Neurol Surg B Skull Base. 2016 Feb;77(1):61-5. doi: 10.1055/s-0035-1560047. Epub 2015 Aug 20.
9
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma.国际骨髓瘤工作组更新了多发性骨髓瘤的诊断标准。
Lancet Oncol. 2014 Nov;15(12):e538-48. doi: 10.1016/S1470-2045(14)70442-5. Epub 2014 Oct 26.
10
Sclerotic multiple myeloma with an unusual sunburst periosteal reaction occurring in the sternum.硬化性多发性骨髓瘤,伴有胸骨出现罕见的日光放射状骨膜反应。
Skeletal Radiol. 2015 May;44(5):749-54. doi: 10.1007/s00256-014-2036-x. Epub 2014 Oct 29.