粘质沙雷氏菌临床分离株的抗菌药敏性
Antimicrobial susceptibility of clinical isolates of Serratia marcescens.
作者信息
Alvarez J S, Regueiro B, Garrido M J
出版信息
Antimicrob Agents Chemother. 1979 Oct;16(4):523-4. doi: 10.1128/AAC.16.4.523.
The in vitro susceptibilities of 242 isolates of Serratia marcescens to 17 antibacterial drugs have been determined. Oxolinic acid, nalidixic acid, cefoxitin, and amikacin were the most active drugs. Ampicillin, kanamycin, and cephalothin were among the least active. A 4-year study showed that resistance of S. marcescens to dibekacin, tobramycin, sisomycin, and gentamicin has increased at least one order of magnitude in that period, whereas resistance to amikacin showed but a twofold increase.
已测定了242株粘质沙雷氏菌对17种抗菌药物的体外敏感性。恶喹酸、萘啶酸、头孢西丁和阿米卡星是活性最强的药物。氨苄西林、卡那霉素和头孢噻吩活性最弱。一项为期4年的研究表明，在那段时期，粘质沙雷氏菌对双去氧卡那霉素、妥布霉素、西索米星和庆大霉素的耐药性至少增加了一个数量级，而对阿米卡星的耐药性仅增加了两倍。
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