Divisão de Medicina Veterinária, Guarda Nacional Republicana (GNR), Rua Presidente Arriaga 9, Lisbon, 1200-771, Portugal.
Faculty of Veterinary Medicine, Lusófona University, Lisbon, Portugal.
Lasers Med Sci. 2024 Aug 8;39(1):211. doi: 10.1007/s10103-024-04164-2.
To evaluate the effect of post-surgical photobiomodulation therapy in dogs.
Twenty dogs were selected for elective gastropexy and randomly divided into a control (CG, n = 10) and a PBMT group (PBMTG, n = 10). Pre‑medication consisted of medetomidine and butorphanol. Meloxicam was administered before the procedure. Induction was performed with propofol and maintained with sevoflurane. Local blocks with lidocaine were used. Incisional gastropexy was performed in all animals. PBMTG received PBMT immediately after surgery. The need for postoperative rescue analgesia, if the animal had eaten by the evaluation momen, and pain scores were collected using the Glasgow Composite Measure Pain Scale - Short Form (CMPS‑SF) at 1, 2, 4, 6, 8, 12, 16, 20, and 24 h post‑endotracheal extubation. CMPS‑SF scores were compared with the Mann-Whitney Test and proportions of animals that required rescue analgesia and had eaten with a χ test. P was set at < 0.05.
No rescue analgesia was needed for any animal. Still, significant differences were observed in CMPS-SF scores between CG and PBMTG between 1 and 4 h post-extubation. PBMTG had a significantly higher proportion of animals eating up to the 8 h post-extubation evaluation moment.
Adding post-surgical photobiomodulation to a standard anesthesia and analgesia protocol reduced CMPS-SF scores and increased the proportion of animals that resumed eating compared to the standard protocol alone.
评估手术后光生物调节疗法对犬的疗效。
选择 20 只狗进行择期胃固定术,并随机分为对照组(CG,n = 10)和 PBMT 组(PBMTG,n = 10)。术前用药包括甲磺酸右美托咪定和布托啡诺。在手术前给予美洛昔康。诱导使用丙泊酚,维持使用七氟醚。使用利多卡因进行局部阻滞。所有动物均进行切口胃固定术。PBMTG 在手术后立即接受 PBMT。记录术后需要解救镇痛的情况,如果动物在评估时已经进食,并使用格拉斯哥复合疼痛量表-短表(CMPS-SF)在气管拔管后 1、2、4、6、8、12、16、20 和 24 小时评估疼痛评分。使用曼-惠特尼检验比较 CMPS-SF 评分,使用卡方检验比较需要解救镇痛和进食的动物比例。P 值设定为< 0.05。
没有动物需要解救镇痛。然而,在气管拔管后 1 至 4 小时,CG 和 PBMTG 之间的 CMPS-SF 评分存在显著差异。PBMTG 组在气管拔管后 8 小时评估时,进食的动物比例显著更高。
与单独使用标准麻醉和镇痛方案相比,在标准麻醉和镇痛方案中添加术后光生物调节治疗可降低 CMPS-SF 评分,并增加恢复进食的动物比例。