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60 岁以下髋部骨折成年人的酒精和药物使用情况——验证工具与临床观察的比较:218 例患者的前瞻性多中心队列研究。

Alcohol and drug use in adults younger than 60 years with hip fracture - A comparison of validated instruments and the clinical eye: A prospective multicenter cohort study of 218 patients.

机构信息

Department of Orthopaedics Lund University, Skåne University Hospital, Malmö, Sweden.

Institute for Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.

出版信息

Injury. 2024 Oct;55(10):111765. doi: 10.1016/j.injury.2024.111765. Epub 2024 Aug 2.

Abstract

BACKGROUND

It is a common preconception that young individuals sustaining hip fractures have alcohol and/or drug use disorder. It is important to evaluate the actual use to avoid complications and plan the rehabilitation.

AIM

The primary objective was to assess alcohol and drug consumption in hip fracture patients <60 years using the validated Alcohol Use Disorders Identification Test (AUDIT) and Drug Use Disorders Identification Test (DUDIT) scores. We secondarily investigated the agreement between the instruments and the physicians' clinical evaluation of usage.

MATERIAL AND METHODS

This is a sub-study of 91 women and 127 men from a multicenter cohort study of patients with an acute hip fracture treated at four hospitals in Denmark and Sweden. AUDIT and DUDIT forms were completed by the patients. In addition, the researchers made an evaluation of the patients' alcohol/drug use based on direct patient contact and information on previous alcohol/drug use from medical charts. AUDIT ranges 0-40 with 6 (women) and 8 (men) as the cut-off for hazardous use. DUDIT ranges 0-44 with cut-offs of 2 and 6 indicating drug-related problems.

RESULTS

According to the AUDIT, 29 % of the patients had a hazardous alcohol use (25 % women, 31 % men), whilst the clinical evaluation identified 26 % (24 % women, 28 % men). However, there was a low agreement between "the clinical eye" and AUDIT, as the clinical evaluation only correctly identified 35 of 56 individuals with AUDIT-scores indicating hazardous alcohol use. DUDIT equaled drug related problems in 8 % (5 % women, 10 % men), the clinical evaluation depicted 8 % with drug related problems (4 % women, 10 % men). The agreement was low between "the clinical eye" and DUDIT; only 7 of 15 with DUDIT-scores indicating drug related problems were correctly identified.

CONCLUSION

Hazardous alcohol consumption is more common in non-elderly hip fracture patients than in the general population. Considering both self-reported alcohol use and clinical evaluation, women have almost as high rate as men. DUDIT indicated drug related problems to be slightly more common than in the population. Still, a majority did not exhibit troublesome use of neither alcohol nor drugs. The two screening methods do not identify the same individuals, and further investigation in clinical practice is needed.

摘要

背景

人们普遍认为,年轻的髋部骨折患者有酗酒和/或药物使用障碍。评估实际使用情况以避免并发症并规划康复非常重要。

目的

主要目的是使用经过验证的酒精使用障碍识别测试 (AUDIT) 和药物使用障碍识别测试 (DUDIT) 评分评估<60 岁髋部骨折患者的酒精和药物使用情况。我们还调查了这些工具与医生对使用情况的临床评估之间的一致性。

材料和方法

这是一项来自丹麦和瑞典四家医院治疗的急性髋部骨折患者多中心队列研究的亚研究,共纳入 91 名女性和 127 名男性患者。患者填写 AUDIT 和 DUDIT 表格。此外,研究人员根据直接与患者接触以及从病历中获得的先前酒精/药物使用信息,对患者的酒精/药物使用情况进行评估。AUDIT 评分为 0-40,女性为 6(女性),男性为 8(男性)为危险使用的界限。DUDIT 评分为 0-44,界限为 2 和 6,表明存在与药物相关的问题。

结果

根据 AUDIT,29%的患者存在危险的酒精使用(女性 25%,男性 31%),而临床评估发现 26%(女性 24%,男性 28%)。然而,“临床眼光”和 AUDIT 之间的一致性较低,因为临床评估仅正确识别了 56 名 AUDIT 评分表明危险饮酒的人中的 35 人。DUDIT 显示 8%的人存在与药物相关的问题(女性 5%,男性 10%),而临床评估显示 8%的人存在与药物相关的问题(女性 4%,男性 10%)。“临床眼光”和 DUDIT 之间的一致性较低;只有 15 名 DUDIT 评分表明存在与药物相关的问题的人中,有 7 人被正确识别。

结论

非老年髋部骨折患者中危险饮酒比一般人群更为常见。考虑到自我报告的酒精使用情况和临床评估,女性的发生率几乎与男性相同。DUDIT 表明与药物相关的问题比一般人群略为常见。尽管如此,大多数人既没有出现酒精也没有出现药物使用问题。两种筛选方法并不能识别出相同的个体,在临床实践中需要进一步调查。

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