Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, Anguita Montserrat, Innocenti Matteo Lorenzo, Tarrés-Call Jordi, Pettenati Elisa
EFSA J. 2024 Aug 8;22(8):e8951. doi: 10.2903/j.efsa.2024.8951. eCollection 2024 Aug.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the feed additive consisting of endo-1,4-beta-xylanase (produced with MUCL 49755) and endo-1,3(4)-beta-glucanase (produced with MUCL 49754) (AveMix® XG 10/AveMix® XG 10 L) for the renewal of its authorisation as zootechnical feed additive for pigs for fattening, minor porcine species for fattening and turkeys for fattening. The applicant declared a change in the carrier material used in AveMix® XG 10 from soybean meal to calcium carbonate + wheat flour or calcium carbonate + sepiolite. The applicant provided evidence that the additive Avemix® XG 10 with calcium carbonate + wheat flour and Avemix® XG 10 L comply with the conditions of the authorisation. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) noted that no data were submitted to support compliance of the formulation of Avemix® XG 10 with calcium carbonate + sepiolite with the conditions of the authorisation. The FEEDAP Panel concluded that both forms of the additive remain safe for pigs for fattening, minor porcine species for fattening and turkeys for fattening, consumers and the environment. Regarding the safety for the user, Avemix® XG 10 formulated with calcium carbonate + sepiolite and Avemix® XG 10 L are not irritant to skin and eyes. No conclusions on the irritation potential of Avemix® XG 10 formulated with calcium carbonate + wheat flour could be drawn. The additive in all its formulations is considered a respiratory and skin sensitiser. There was no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就一种饲料添加剂提供科学意见，该添加剂由内切-1,4-β-木聚糖酶（由MUCL 49755生产）和内切-1,3(4)-β-葡聚糖酶（由MUCL 49754生产）组成（AveMix® XG 10/AveMix® XG 10 L），用于其作为育肥猪、育肥小型猪种和育肥火鸡的动物营养饲料添加剂授权的续展。申请人声明AveMix® XG 10中使用的载体材料已从豆粕改为碳酸钙+小麦粉或碳酸钙+海泡石。申请人提供了证据，证明含有碳酸钙+小麦粉的添加剂Avemix® XG 10和Avemix® XG 10 L符合授权条件。欧洲食品安全局动物饲料添加剂和产品或物质专家小组（FEEDAP）指出，未提交数据以支持含有碳酸钙+海泡石的Avemix® XG 10配方符合授权条件。FEEDAP小组得出结论，该添加剂的两种形式对育肥猪、育肥小型猪种和育肥火鸡、消费者和环境而言仍然是安全的。关于对使用者的安全性，含有碳酸钙+海泡石的Avemix® XG 10配方和Avemix® XG 10 L对皮肤和眼睛无刺激性。对于含有碳酸钙+小麦粉的Avemix® XG 10的刺激潜力无法得出结论。该添加剂的所有配方均被视为呼吸道和皮肤致敏剂。在授权续展的背景下，无需评估该添加剂的功效。
