Tam Pui Kit, Oey Nicodemus Edrick, Tang Ning, Ramamurthy Guhan, Chew Effie
Division of Rehabilitation Medicine, Department of Medicine, National University Hospital, Singapore 119228, Singapore.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117549, Singapore.
J Clin Med. 2024 Jul 28;13(15):4420. doi: 10.3390/jcm13154420.
Upper limb weakness following stroke poses a significant global psychosocial and economic burden. Non-invasive brain stimulation (NIBS) is a potential adjunctive treatment in rehabilitation. However, traditional approaches to rebalance interhemispheric inhibition may not be effective for all patients. The supportive role of the contralesional hemisphere in recovery of upper limb motor function has been supported by animal and clinical studies, particularly for those with severe strokes. This review aims to provide an overview of the facilitation role of the contralesional hemisphere for post-stroke motor recovery. While more studies are required to predict responses and inform the choice of NIBS approach, contralesional facilitation may offer new hope for patients in whom traditional rehabilitation and NIBS approaches have failed.
中风后上肢无力给全球带来了巨大的心理社会和经济负担。非侵入性脑刺激（NIBS）是康复治疗中一种潜在的辅助治疗方法。然而，传统的重新平衡半球间抑制的方法可能并非对所有患者都有效。动物和临床研究支持了对侧半球在恢复上肢运动功能中的支持作用，尤其是对于那些患有严重中风的患者。本综述旨在概述对侧半球在中风后运动恢复中的促进作用。虽然需要更多的研究来预测反应并指导NIBS方法的选择，但对侧促进可能为那些传统康复和NIBS方法均无效的患者带来新的希望。
