National Research Council (CNR), Institute of Biosciences and BioResources (IBBR), Via P. Castellino 111, 80131 Naples, Italy.
Institute for Veterinary and Agri-Food Bioethics (IBV-A), 00054 Fiumicino, Italy.
Molecules. 2024 Jul 30;29(15):3594. doi: 10.3390/molecules29153594.
Research studies on plant secondary metabolites have increased over the last decades as a consequence of the growing consumer demand for natural products in pharmaceutics and therapeutics, as well as in perfumery and cosmetics. In this perspective, many Mediterranean plant species could be an appreciated source of bioactive compounds with pharmacological and health-promoting properties, including antioxidant, antimicrobial, antiviral, anti-inflammatory, and antitumor ones. and are commercially important plants of the Mediterranean flora, with great therapeutic use in the treatment of many disorders since ancient times, and are now listed in several world pharmacopoeias and drug agencies. The present review offers an overview of the main phytochemicals, phenols, terpenes, and alkaloids, biosynthesized in and , both species endemic to the Mediterranean region. Further, all current knowledge and scientific data on taxonomic classification, botanical description, traditional uses, pharmacological studies, and potential toxicity of both species were reported. The principal aim of this review is to point out the prospective use of and as valuable reservoirs of beneficial plant-derived products with interesting biological properties, also providing suggestions and future challenges for the full exploitation of these two Mediterranean species for human life improvement.
过去几十年来，由于消费者对制药和治疗、香水和化妆品领域天然产品的需求不断增长，对植物次生代谢产物的研究有所增加。从这个角度来看，许多地中海植物物种可能是具有药理和促进健康特性的生物活性化合物的重要来源，包括抗氧化剂、抗菌、抗病毒、抗炎和抗肿瘤特性。 和 是地中海植物群中具有商业重要性的植物，自古以来就在治疗许多疾病方面具有巨大的治疗用途，现在被列入世界上几个药典和药物机构。本综述概述了 和 中生物合成的主要植物化学物质、酚类、萜类和生物碱，这两个物种都是地中海地区特有的。此外，还报告了关于这两个物种的分类学分类、植物学描述、传统用途、药理学研究和潜在毒性的所有现有知识和科学数据。本综述的主要目的是指出 和 作为具有有趣生物特性的有益植物衍生产品的有价值的资源的潜在用途，并为充分利用这两个地中海物种以改善人类生活提出建议和未来挑战。
