微结构反应器中酯化和酯交换反应的动力学研究

Kinetic Aspects of Esterification and Transesterification in Microstructured Reactors.

作者信息

Yao Xingjun, Wang Zhenxue, Qian Ming, Deng Qiulin, Sun Peiyong

机构信息

Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.

School of Materials Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China.

出版信息

Molecules. 2024 Aug 1;29(15):3651. doi: 10.3390/molecules29153651.

DOI:10.3390/molecules29153651

PMID:39125055

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11314161/

Abstract

Microstructured reactors offer fast chemical engineering transfer and precise microfluidic control, enabling the determination of reactions' kinetic parameters. This review examines recent advancements in measuring microreaction kinetics. It explores kinetic modeling, reaction mechanisms, and intrinsic kinetic equations pertaining to two types of microreaction: esterification and transesterification reactions involving acids, bases, or biocatalysts. The utilization of a micro packed-bed reactor successfully achieves a harmonious combination of the micro-dispersion state and the reaction kinetic characteristics. Additionally, this review presents micro-process simulation software and explores the advanced integration of microreactors with spectroscopic analyses for reaction monitoring and data acquisition. Furthermore, it elaborates on the control principles of the micro platform. The superiority of online measurement, automation, and the digitalization of the microreaction process for kinetic measurements is highlighted, showcasing the vast prospects of artificial intelligence applications.

摘要

微结构反应器具有快速的化学工程传递和精确的微流体控制能力，能够测定反应的动力学参数。本综述考察了微反应动力学测量的最新进展。它探讨了与两种微反应（即涉及酸、碱或生物催化剂的酯化和酯交换反应）相关的动力学建模、反应机理和本征动力学方程。微填充床反应器的应用成功实现了微分散状态与反应动力学特性的和谐结合。此外，本综述介绍了微过程模拟软件，并探讨了微反应器与光谱分析的先进集成，用于反应监测和数据采集。此外，还阐述了微平台的控制原理。突出了微反应过程动力学测量在线测量、自动化和数字化的优势，展示了人工智能应用的广阔前景。