Phillips G, Vickers M D
Br J Anaesth. 1979 Oct;51(10):961-5. doi: 10.1093/bja/51.10.961.
Three comparable groups of surgical patients were given nefopam 0.2 mg kg-1 or 0.4 mg kg-1 or morphine 0.15 mg kg-1 for pain relief after operation. Nefopam 0.4 mg kg-1 was equi-analgesic with morphine 0.15 mg kg-1 and produced no obvious cardiovascular or respiratory side-effects.
三组具有可比性的外科手术患者在术后分别给予奈福泮0.2毫克/千克或0.4毫克/千克或吗啡0.15毫克/千克以缓解疼痛。奈福泮0.4毫克/千克与吗啡0.15毫克/千克镇痛效果相当，且未产生明显的心血管或呼吸副作用。
