Saha S K
Postgrad Med J. 1981 Nov;57(673):686-9. doi: 10.1136/pgmj.57.673.686.
Postoperative analgesia, once established initially by the titration method, is sustained with a flexible regime of papaveretum, infused continuously with a portable syringe pump. The initial analgesic requirement (IAR) for titrating the pain threshold level, was between 4 and 10 mg of papaveretum and the maintenance dose between 1 and 1·66 mg/hr for the first 24 hr and between 0·83 and 1 mg/hr for the second 24 hr. There was no significant association between IAR and the maintenance dose (<0·2) nor was there any correlation between the maintenance dose, body weight, age, sex or nature of operations. The results in 70 patients are encouraging.
术后镇痛最初通过滴定法确定后，采用灵活的吗啡制度维持，使用便携式注射泵持续输注。滴定疼痛阈值水平的初始镇痛需求量（IAR）为4至10毫克吗啡，前24小时的维持剂量为每小时1至1.66毫克，后24小时为每小时0.83至1毫克。IAR与维持剂量之间无显著关联（<0.2），维持剂量与体重、年龄、性别或手术性质之间也无相关性。70例患者的结果令人鼓舞。
