Biotic and abiotic stresses have already seriously restricted the growth and development of , thereby influencing the quality and yield of its wood and turpentine. Recent studies have shown that C2H2 zinc finger protein transcription factors play an important role in biotic and abiotic stress response. However, the members and expression patterns of C2H2 TFs in response to stresses in have not been performed. In this paper, 57 C2H2 zinc finger proteins of were identified and divided into five subgroups according to a phylogenetic analysis. In addition, six Q-type containing the plant-specific motif 'QALGGH' were selected for further study under different stresses. The findings demonstrated that exhibit responsiveness towards various abiotic stresses, including drought, NaCl, ABA, PEG, HO, etc., as well as biotic stress caused by the pine wood nematode. In addition, and were nuclear localization proteins, and was a transcriptional activator. was selected as a potential transcriptional regulator in response to various stresses in . These findings laid a foundation for further study on the role of in stress tolerance.