Department of Psychological and Brain Sciences, University of Massachusetts, Amherst, MA, USA.
Department of Psychology, Virginia Tech, Blacksburg, VA, USA.
J Youth Adolesc. 2024 Nov;53(11):2654-2668. doi: 10.1007/s10964-024-02065-9. Epub 2024 Aug 10.
It is unknown how the Addictions Neuroclinical Assessment markers-negative affect, sensation seeking, and executive function-contribute to substance use development. This study examined whether associations of negative affect and sensation seeking with substance use vary by executive function. Participants were 167 adolescents (47% female) who participated annually for four years (M = 14.07, SD = 0.54 at Time 1). There were within-person bidirectional associations between higher negative affect and higher substance use for adolescents with lower executive function. Adolescents with higher sensation seeking at age 14 exhibited increasing substance use trajectories from age 14 to 17, regardless of executive function level. Negative affect and substance use influence each other within individuals, whereas sensation seeking predicts substance use between individuals.
目前尚不清楚成瘾神经临床评估标志物——负性情绪、感觉寻求和执行功能——如何促进物质使用的发展。本研究旨在探讨负性情绪和感觉寻求与物质使用的关联是否因执行功能而异。研究对象为 167 名青少年（47%为女性），他们在四年内每年参与一次研究（第一次测试时的平均年龄为 14.07 岁，标准差为 0.54）。对于执行功能较低的青少年，较高的负性情绪与较高的物质使用之间存在个体内的双向关联。在 14 岁时表现出较高感觉寻求的青少年，无论执行功能水平如何，其物质使用轨迹均从 14 岁到 17 岁呈现上升趋势。负性情绪和物质使用在个体内部相互影响，而感觉寻求则在个体之间预测物质使用。
