Benzerroug E H, Wery M
Rev Epidemiol Sante Publique. 1985;33(4-5):276-82.
The residual focus of Khemis el Kechna represented in 1981 nearly the totality of the autochtonous cases detected in Algeria that year (51 cases/53 cases). Control measures were applied during 3 successive years, the number of cases dropped from 51 in 1981 to 18 in 1982 and to 0 in 1983. In order to confirm the interruption of malaria transmission a sero-epidemiological study was carried out in 1984. The analysis of serological results by age, time and place of residence led to the conclusion that malaria transmission no longer occurs. A comparison of the serological results obtained by two blood sampling techniques (serum/dried blood on filter paper) confirmed the reliability of the results when eluted dried blood is used. A statistically significant difference was observed between the proportions of positives sera according to the antigen species used (P. falciparum culture strain or P. vivax obtained from patient originating from India.
1981年，凯米斯-凯什纳的残余疫源地几乎占当年阿尔及利亚本土检测到的所有病例（51例/53例）。连续三年采取了控制措施，病例数从1981年的51例降至1982年的18例，并于1983年降至0例。为了确认疟疾传播是否中断，1984年开展了一项血清流行病学研究。按年龄、时间和居住地点对血清学结果进行分析后得出结论，疟疾传播已不再发生。对两种采血技术（血清/滤纸上的干血）获得的血清学结果进行比较，证实了使用洗脱干血时结果的可靠性。根据所用抗原种类（恶性疟原虫培养株或来自印度患者的间日疟原虫），阳性血清比例之间存在统计学上的显著差异。
