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伊朗北部、西北部和西南部疟疾的间接荧光抗体血清学调查。

IFA serological surveys of malaria in north, north-west and south-west parts of Iran.

作者信息

Edrissian G H, Ghorbani M, Afshar A

出版信息

Bull Soc Pathol Exot Filiales. 1985;78(3):349-59.

PMID:3896549
Abstract

In the IFA serological surveys of malaria carried out in north, north-west and south-west parts of Iran during 1975-1982 altogether 9,132 subjects were studied for malaria antibodies and parasitaemia. Serological data indicated probable malaria transmission in a consolidation area where the autochthonous cases of malaria were reported a year after this serological study. Asymptomatic parasite carriers of P. malariae were found by IFA and parasite concentration techniques among the professional blood donors and the residents of a village without any recent malaria history. IFA results with P. falciparum antigen reflected the malaria histories in the studied areas of west Azerbaijan better than P. vivax antigen. The serological and parasitological findings in the nomads of Bakhtiary tribes showed that the nomads are more exposed to malaria infection in the winter quarters of Izeh area and they are also more under malaria control programme when they are living in this area. In comparison of IFA results of 438 paired plasma and dried blood samples tested with P. vivax and P. falciparum antigens, there was no significant difference between SPR in plasma and dried blood samples, however in the dried blood samples collected by malaria surveillance agents on filter paper SPR and GMRT were considerably low.

摘要

在1975 - 1982年期间于伊朗北部、西北部和西南部开展的疟疾间接荧光抗体试验(IFA)血清学调查中,共对9132名受试者进行了疟疾抗体和疟原虫血症检测。血清学数据表明,在一个巩固地区可能存在疟疾传播,在该血清学研究一年后报告了当地的疟疾病例。通过IFA和寄生虫浓缩技术,在职业献血者以及一个近期无疟疾病史村庄的居民中发现了间日疟原虫无症状寄生虫携带者。用恶性疟原虫抗原进行IFA检测的结果,比用间日疟原虫抗原能更好地反映西阿塞拜疆研究地区的疟疾病史。巴赫蒂亚里部落游牧民的血清学和寄生虫学研究结果表明,游牧民在伊泽赫地区的冬季营地更容易感染疟疾,而且当他们生活在该地区时,也更受疟疾控制项目的影响。在用间日疟原虫和恶性疟原虫抗原检测的438对血浆和干血样本的IFA结果比较中,血浆和干血样本的血清阳性率(SPR)之间没有显著差异,然而,疟疾监测人员在滤纸上采集的干血样本中,SPR和几何平均滴度(GMRT)相当低。

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